Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 6/20 | 0.46 |
| ▸ | AR | P10275 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.39 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.39 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.39 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.39 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.39 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.39 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18768164 | 0.92 | AKR1C3 (0.42) | AKR1C3ARSLC6A2SLC6A4MEN1 | |
| SCHEMBL18768208 | 0.90 | MEN1 (0.43) | AKR1C3ARMEN1KMT2A | |
| SCHEMBL18767864 | 0.90 | AKR1C3 (0.48) | AKR1C3ARMEN1KMT2A | |
| SCHEMBL18768456 | 0.90 | AKR1C3 (0.42) | AKR1C3ARSLC6A2SLC6A4 | |
| SCHEMBL18768438 | 0.87 | AKR1C3 (0.47) | AKR1C3ARSLC6A2SLC6A4MEN1 | |
| SCHEMBL18768448 | 0.85 | AKR1C3 (0.45) | AKR1C3ARMEN1KMT2A | |
| SCHEMBL18768634 | 0.85 | HRH4 (0.55) | AKR1C3ARSLC6A2SLC6A4GRIN2D | |
| SCHEMBL18766913 | 0.83 | AKR1C3 (0.44) | AKR1C3ARMEN1KMT2A | |
| SCHEMBL18768638 | 0.83 | MDM2 (0.49) | AKR1C3 | |
| SCHEMBL18768600 | 0.83 | AKR1C3 (0.40) | AKR1C3MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017066705-A1 | COMPOUNDS, COMPOSITIONS AND METHODS OF USE AGAINST STRESS GRANULES | AQUINNAH PHARMACEUTICALS, INC. (US) | 2017-04-20 | — | — | WO | disclosed |