Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | KDM1A | O60341 | 2/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | HTR2B | P41595 | 1/20 | 0.35 |
| ▸ | PDE2A | O00408 | 1/20 | 0.35 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.34 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.34 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.34 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.34 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.34 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL18742684 | 0.98 | SLC6A4 (0.37) | HDAC3HDAC1HDAC2HDAC6SLC6A4 | |
| SCHEMBL13229765 | 0.92 | HDAC6 (0.39) | HDAC3HDAC1HDAC2HDAC6SLC6A4 | |
| SCHEMBL18769481 | 0.85 | KDM1A (0.39) | HDAC6SLC6A4SLC6A3KDM1APSEN1 | |
| SCHEMBL18717566 | 0.84 | OPRL1 (0.38) | HDAC3HDAC1HDAC2HDAC6SLC6A4 | |
| Hydrochloric Acid SCHEMBL18742535 | 0.84 | KDM1A (0.38) | HDAC6SLC6A4SLC6A3KDM1AHTR2A | |
| SCHEMBL18769595 | 0.81 | SLC6A4 (0.54) | SLC6A4SLC6A3KDM1A | |
| SCHEMBL15934498 | 0.81 | BACE1 (0.43) | KDM1A | |
| SCHEMBL3024298 | 0.80 | CYP2C9 (0.38) | SLC6A4SLC6A3 | |
| Hydrochloric Acid SCHEMBL18742635 | 0.79 | SLC6A4 (0.53) | SLC6A4SLC6A3KDM1A | |
| Hydrochloric Acid SCHEMBL18742430 | 0.79 | BACE1 (0.42) | KDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3362445-B1 | OXADIAZOLE AMINE DERIVATIVE COMPOUNDS AS HISTONE DEACETYLASE 6 INHIBITOR, AND THE PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | CHONG KUN DANG PHARMACEUTICAL CORP (KR) | 2023-01-25 | — | — | EP | disclosed |
| WO-2017065473-A1 | OXADIAZOLE AMINE DERIVATIVE COMPOUNDS AS HISTONE DEACETYLASE 6 INHIBITOR, AND THE PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | CHONG KUN DANG PHARMACEUTICAL CORP. (KR) | 2017-04-20 | — | — | WO | disclosed |