Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 2/20 | 0.39 |
| ▸ | PSEN1 | P49768 | 2/20 | 0.37 |
| ▸ | PSEN2 | P49810 | 2/20 | 0.37 |
| ▸ | APH1B | Q8WW43 | 2/20 | 0.37 |
| ▸ | NCSTN | Q92542 | 2/20 | 0.37 |
| ▸ | APH1A | Q96BI3 | 2/20 | 0.37 |
| ▸ | PSENEN | Q9NZ42 | 2/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL18742535 | 0.98 | KDM1A (0.38) | KDM1APSEN1PSEN2APH1BNCSTN | |
| SCHEMBL18769476 | 0.85 | HDAC3 (0.37) | KDM1APSEN1PSEN2APH1BNCSTN | |
| Hydrochloric Acid SCHEMBL18742684 | 0.84 | SLC6A4 (0.37) | KDM1ASLC6A3SLC6A4HDAC6 | |
| SCHEMBL18769581 | 0.81 | PSEN1 (0.43) | KDM1APSEN1PSEN2APH1BNCSTN | |
| Hydrochloric Acid SCHEMBL18742554 | 0.79 | PSEN1 (0.42) | KDM1APSEN1PSEN2APH1BNCSTN | |
| SCHEMBL15934498 | 0.77 | BACE1 (0.43) | KDM1A | |
| SCHEMBL13229765 | 0.77 | HDAC6 (0.39) | KDM1APSEN1PSEN2APH1BNCSTN | |
| Hydrochloric Acid SCHEMBL18742430 | 0.76 | BACE1 (0.42) | KDM1A | |
| SCHEMBL18742442 | 0.75 | HDAC4 (0.43) | KDM1APSEN1PSEN2APH1BNCSTN | |
| SCHEMBL18742587 | 0.74 | SLC6A4 (0.39) | KDM1APSEN1PSEN2APH1BNCSTN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3362445-B1 | OXADIAZOLE AMINE DERIVATIVE COMPOUNDS AS HISTONE DEACETYLASE 6 INHIBITOR, AND THE PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | CHONG KUN DANG PHARMACEUTICAL CORP (KR) | 2023-01-25 | — | — | EP | disclosed |
| WO-2017065473-A1 | OXADIAZOLE AMINE DERIVATIVE COMPOUNDS AS HISTONE DEACETYLASE 6 INHIBITOR, AND THE PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | CHONG KUN DANG PHARMACEUTICAL CORP. (KR) | 2017-04-20 | — | — | WO | disclosed |