Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 3/20 | 0.40 |
| ▸ | PSEN1 | P49768 | 2/20 | 0.38 |
| ▸ | PSEN2 | P49810 | 2/20 | 0.38 |
| ▸ | APH1B | Q8WW43 | 2/20 | 0.38 |
| ▸ | NCSTN | Q92542 | 2/20 | 0.38 |
| ▸ | APH1A | Q96BI3 | 2/20 | 0.38 |
| ▸ | PSENEN | Q9NZ42 | 2/20 | 0.38 |
| ▸ | BACE1 | P56817 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.38 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL18742676 | 0.98 | KDM1A (0.39) | KDM1APSEN1PSEN2APH1BNCSTN | |
| Hydrochloric Acid SCHEMBL31410053 | 0.85 | SLC6A4 (0.39) | KDM1ABACE1SLC6A4SLC6A3 | |
| SCHEMBL18769581 | 0.82 | PSEN1 (0.43) | KDM1APSEN1PSEN2APH1BNCSTN | |
| Hydrochloric Acid SCHEMBL18742554 | 0.81 | PSEN1 (0.42) | KDM1APSEN1PSEN2APH1BNCSTN | |
| SCHEMBL3026445 | 0.80 | SLC6A9 (0.37) | KDM1ABACE1SLC6A4SLC6A3 | |
| SCHEMBL18769595 | 0.78 | SLC6A4 (0.54) | KDM1ASLC6A4SLC6A3 | |
| SCHEMBL13229767 | 0.78 | SLC6A4 (0.39) | KDM1APSEN1PSEN2APH1BNCSTN | |
| Hydrochloric Acid SCHEMBL18742635 | 0.77 | SLC6A4 (0.53) | KDM1ASLC6A4SLC6A3 | |
| Hydrochloric Acid SCHEMBL18742593 | 0.77 | HTR2A (0.39) | KDM1APSEN1PSEN2APH1BNCSTN | |
| SCHEMBL18769568 | 0.75 | DPP4 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3362445-B1 | OXADIAZOLE AMINE DERIVATIVE COMPOUNDS AS HISTONE DEACETYLASE 6 INHIBITOR, AND THE PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | CHONG KUN DANG PHARMACEUTICAL CORP (KR) | 2023-01-25 | — | — | EP | disclosed |
| WO-2017065473-A1 | OXADIAZOLE AMINE DERIVATIVE COMPOUNDS AS HISTONE DEACETYLASE 6 INHIBITOR, AND THE PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | CHONG KUN DANG PHARMACEUTICAL CORP. (KR) | 2017-04-20 | — | — | WO | disclosed |