SCHEMBL187697

SCHEMBL187697

O=[N+]([O-])c1cccc2cccc([N+](=O)[O-])c12

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.61
TDP1 Q9NUW8 4/20 0.58
GPR35 Q9HC97 2/20 0.56
PDE10A Q9Y233 1/20 0.53
MEN1 O00255 3/20 0.51
KMT2A Q03164 3/20 0.51
KDM4E B2RXH2 2/20 0.51
MAPT P10636 2/20 0.51
GAA P10253 1/20 0.51
HTT P42858 1/20 0.51
L3MBTL1 Q9Y468 1/20 0.51
TSHR P16473 3/20 0.50
SMN1; SMN2 Q16637 2/20 0.50
HSD17B10 Q99714 2/20 0.50
NOS1 P29475 2/20 0.50
NOS2 P35228 2/20 0.50
APEX1 P27695 2/20 0.50
TYMS P04818 1/20 0.50
CYP1A2 P05177 1/20 0.50
CYP3A4 P08684 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29626558 1.00 ALDH1A1 (0.61) ALDH1A1TDP1GPR35PDE10AMEN1
SCHEMBL3038868 0.89 ALDH1A1 (0.52) ALDH1A1TDP1GPR35PDE10AMEN1
Acetone SCHEMBL27618861 0.89 TDP1 (0.52) ALDH1A1TDP1GPR35PDE10AMEN1
SCHEMBL28158962 0.88 ALDH1A1 (0.85) ALDH1A1TDP1GPR35PDE10AMEN1
Pyrene SCHEMBL27684019 0.86 ALDH1A1 (0.63) ALDH1A1TDP1GPR35PDE10AMEN1
SCHEMBL9055141 0.85 ALDH1A1 (0.52) ALDH1A1TDP1GPR35PDE10AMEN1
SCHEMBL2927810 0.85 GPR35 (0.60) ALDH1A1TDP1GPR35PDE10AMEN1
SCHEMBL17283584 0.85 ALDH1A1 (0.52) ALDH1A1TDP1GPR35PDE10AMEN1
SCHEMBL5068468 0.85 ALDH1A1 (0.52) ALDH1A1TDP1GPR35PDE10AMEN1
SCHEMBL6493644 0.85 TSHR (0.62) ALDH1A1TDP1GPR35PDE10AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 338 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118255668-A Process method for producing 1, 5-dinitronaphthalene and 1, 8-dinitronaphthalene by continuous nitration 沈阳化工研究院有限公司 2024-06-28 CN claimed
CN-115057783-A Method for separating 1, 5-diaminonaphthalene and 1, 8-diaminonaphthalene 宁夏瑞泰科技股份有限公司 2022-09-16 CN claimed
WO-2021108901-A1 NITRO-SUBSITUTED AROMATIC COMPOUNDS FOR USE IN ELECTRODES VALORBEC, S.E.C. (CA) 2021-06-10 WO claimed
CN-111116378-A Method for synthesizing 1, 8-diaminonaphthalene by selective reduction of 1, 8-dinitronaphthalene 南京金浩医药科技有限公司 2020-05-08 CN claimed
CN-108686652-B 1, 8-dinitronaphthalene hydrogenation catalyst and preparation method thereof 南通龙翔新材料科技股份有限公司 2019-10-18 CN claimed
CN-108686652-A 1, 8-dinitronaphthalene hydrogenation catalyst and preparation method thereof 南通龙翔新材料科技股份有限公司 2018-10-23 CN claimed
CN-108689863-A A method of preparing 5,6,7,8- tetrahydrochysenes-naphthalidine by raw material of 1,8- dinitronaphthalene 浙江工业大学 2018-10-23 CN claimed
CN-108586270-A A method of preparing 5,6,7,8- tetrahydrochysenes-naphthalidine by raw material of 1,8- diaminonaphthalenes 浙江工业大学 2018-09-28 CN claimed
CN-106977406-A The method of continuous autoclave catalytic hydrogenation synthesizing amino naphthalene 江苏华达化工集团有限公司 2017-07-25 CN claimed
CN-106467467-A A kind of method that fixed bed continuous catalytic hydrogenation prepares diaminonaphthalene 南通龙翔化工有限公司 2017-03-01 CN claimed
US-20050107646-A1 Process for the production of 1,5-dinitronaphthalene BAYER MATERIALSCIENCE AG (DE) 2005-05-19 US claimed
EP-1529772-A1 Process for the production of 1,5-dinitronaphthalene Bayer MaterialScience AG (DE) 2005-05-11 EP claimed
US-6242656-B1 REACTING NITRONAPHTALENE WITH NITRIC ACID IN THE PRESENCE OF A SOLID PERFLUORINATED STRONGLY ACIDIC ION EXCHANGER BAYER AKTIENGESELLSCHAFT (DE) 2001-06-05 US claimed
EP-1015414-A1 METHOD FOR PRODUCING A DINITRONAPHTHALENE-ISOMER MIXTURE HAVING A HIGH 1,5-DINITRONAPHTHALENE PROPORTION BAYER AG (DE) 2000-07-05 EP claimed
WO-1999012887-A1 METHOD FOR PRODUCING A DINITRONAPHTHALENE-ISOMER MIXTURE HAVING A HIGH 1,5-DINITRONAPHTHALENE PROPORTION BAYER AKTIENGESELLSCHAFT (DE) 1999-03-18 WO claimed
WO-1999012886-A1 METHOD FOR PRODUCING A DINITRONAPHTHALENE-ISOMER MIXTURE WITH A HIGH PROPORTION OF 1,5-DINITRONAPHTHALENE BAYER AKTIENGESELLSCHAFT (DE) 1999-03-18 WO claimed
CN-1194972-A Process for preparing 1,5-dinitro naphthalene and 1,8-dinitro naphthalene UNIV SHENYANG POLYTECHNIC (CN) 1998-10-07 CN claimed
US-5663030-A A PHENYL OR NORBORNANE DERIVATIVE AS AN ADDITIVE TO REDUCE HEAT AND ENERGY REQUIRED TO FUSE THE TONER AND TO REDUCE JAMMING OF THE EQUIPMENT XEROX CORPORATION (US) 1997-09-02 US claimed
US-4157445-A Method for the preparation of quinoline and aniline compounds UNION CARBIDE CORPORATION (US) 1979-06-05 US claimed
US-4053526-A PROCESS FOR ISOLATING DINITRONAPHTHALENES BAYER AKTIENGESELLSCHAFT (DT) 1977-10-11 US claimed