Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.54 |
| ▸ | CNR1 | P21554 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.51 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.50 |
| ▸ | HRH1 | P35367 | 2/20 | 0.50 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.50 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.50 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.50 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.50 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.50 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.49 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5758747 | 0.98 | DPP7 (0.66) | DPP7ALDH1A1KDM4EGAASMN1; SMN2 | |
| SCHEMBL18769662 | 0.98 | DPP7 (0.70) | DPP7ALDH1A1KDM4EGAASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL5760498 | 0.97 | DPP7 (0.68) | DPP7ALDH1A1KDM4EGAASMN1; SMN2 | |
| SCHEMBL5867373 | 0.95 | DPP7 (0.62) | DPP7ALDH1A1KDM4EGAASMN1; SMN2 | |
| SCHEMBL4419042 | 0.94 | DPP7 (0.64) | DPP7ALDH1A1KDM4EGAASMN1; SMN2 | |
| SCHEMBL12332378 | 0.91 | DPP7 (0.59) | DPP7KDM4EGAASMN1; SMN2SIGMAR1 | |
| SCHEMBL3171554 | 0.91 | DPP7 (0.79) | DPP7SIGMAR1KMT2AHRH3SCN5A | |
| SCHEMBL3165932 | 0.89 | DPP7 (0.82) | DPP7SIGMAR1KMT2AHRH3MCHR1 | |
| SCHEMBL4551826 | 0.86 | MCHR1 (0.53) | DPP7ALDH1A1KDM4ESIGMAR1CHRM2 | |
| Hydrochloric Acid SCHEMBL6341357 | 0.86 | CHRM2 (0.60) | DPP7GAASMN1; SMN2SIGMAR1CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10669305-B2 | C-3 novel triterpenone with C-28 urea derivatives as HIV inhibitors | HETERO LABS LIMITED (IN) | 2020-06-02 | — | — | US | disclosed |
| US-10669305-B2 | C-3 novel triterpenone with C-28 urea derivatives as HIV inhibitors | HETERO LABS LIMITED (IN) | 2020-06-02 | — | — | US | disclosed |
| US-20180305398-A1 | C-3 NOVEL TRITERPENONE WITH C-28 UREA DERIVATIVES AS HIV INHIBITORS | HETERO RESEARCH FOUNDATION (IN) | 2018-10-25 | — | — | US | disclosed |
| WO-2017064628-A1 | C-3 NOVEL TRITERPENONE WITH C-28 UREA DERIVATIVES AS HIV INHIBITORS | HETERO RESEARCH FOUNDATION (IN) | 2017-04-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180305398-A1 | C-3 NOVEL TRITERPENONE WITH C-28 UREA DERIVATIVES AS HIV INHIBITORS | CCR3, CCND3, UBE2D3 | DPP7 1661/4885ALDH1A1 2589/4885KDM4E 2069/4885 |
| US-10669305-B2 | C-3 novel triterpenone with C-28 urea derivatives as HIV inhibitors | CCR3, CCND3, UBE2D3 | DPP7 1661/4885ALDH1A1 2589/4885KDM4E 2069/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.