Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 1/20 | 0.30 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18772017 | 0.87 | — | — | |
| SCHEMBL18772219 | 0.81 | DRD3 (0.32) | — | |
| SCHEMBL18772064 | 0.80 | TLR8 (0.32) | — | |
| SCHEMBL18772202 | 0.80 | — | — | |
| SCHEMBL18772155 | 0.80 | TLR8 (0.34) | TP53HPGD | |
| SCHEMBL18771811 | 0.79 | TLR8 (0.36) | — | |
| SCHEMBL19416285 | 0.79 | — | — | |
| SCHEMBL19416531 | 0.79 | — | — | |
| SCHEMBL19416583 | 0.78 | — | — | |
| SCHEMBL18771950 | 0.75 | TLR8 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3159337-A2 | SUBSTITUTED BENZOAZEPINES AS TOLL-LIKE RECEPTOR MODULATORS | Ventirx Pharmaceuticals, Inc. (US) | 2017-04-26 | — | — | EP | disclosed |