Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.34 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.34 |
| ▸ | GALR1 | P47211 | 1/20 | 0.34 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.32 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18772219 | 0.88 | DRD3 (0.32) | TLR8 | |
| SCHEMBL18772157 | 0.83 | TLR8 (0.32) | TLR8 | |
| SCHEMBL19416589 | 0.81 | CYP4F2 (0.35) | CYP4F2CYP4A11 | |
| SCHEMBL18772192 | 0.81 | TLR8 (0.31) | TLR8TP53 | |
| SCHEMBL18771991 | 0.81 | TLR8 (0.33) | TLR8 | |
| SCHEMBL18772084 | 0.80 | HCRTR1 (0.30) | TP53HPGD | |
| SCHEMBL18772017 | 0.79 | — | — | |
| SCHEMBL18771979 | 0.79 | TLR8 (0.44) | TLR8TLR7GALR1 | |
| SCHEMBL19416314 | 0.78 | — | — | |
| SCHEMBL19415988 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3159337-A2 | SUBSTITUTED BENZOAZEPINES AS TOLL-LIKE RECEPTOR MODULATORS | Ventirx Pharmaceuticals, Inc. (US) | 2017-04-26 | — | — | EP | disclosed |