Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA9 | Q16790 | 17/20 | 0.57 |
| ▸ | CA1 | P00915 | 16/20 | 0.57 |
| ▸ | CA2 | P00918 | 16/20 | 0.57 |
| ▸ | CA12 | O43570 | 7/20 | 0.55 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.52 |
| ▸ | USP2 | O75604 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | CA7 | P43166 | 2/20 | 0.51 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.47 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13083473 | 0.90 | CA9 (0.55) | CA9CA1CA2CA12CA14 | |
| SCHEMBL12231957 | 0.88 | CA9 (0.72) | CA9CA1CA2CA12CA14 | |
| SCHEMBL14620250 | 0.86 | CA9 (0.54) | CA9CA1CA2CA12CA14 | |
| SCHEMBL17974603 | 0.81 | DNASE1L3 (0.66) | CA9CA1CA2CA12CA14 | |
| SCHEMBL14847588 | 0.81 | USP2 (0.56) | CA9CA1CA2CA12CA14 | |
| SCHEMBL17243936 | 0.80 | DNASE1L3 (0.70) | CA9CA1CA2CA12CA14 | |
| SCHEMBL12060447 | 0.80 | CA9 (0.75) | CA9CA1CA2CA12CA14 | |
| SCHEMBL10014172 | 0.80 | CA9 (0.56) | CA9CA1CA2CA12CA14 | |
| SCHEMBL15828111 | 0.80 | CA9 (0.83) | CA9CA1CA2CA12CA14 | |
| SCHEMBL13097493 | 0.79 | CA9 (0.75) | CA9CA1CA2CA12CA14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3159352-A1 | STITCHED POLYPEPTIDES | President and Fellows of Harvard College (US) | 2017-04-26 | — | — | EP | disclosed |