SCHEMBL18774271

SCHEMBL18774271

CN1CCCCCN(C)C1

nearest known ligand 0.64

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
HRH3 Q9Y5N1 1/20 0.33
MGLL Q99685 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14393594 1.00 HRH3 (0.33) HRH3MGLL
SCHEMBL17771603 1.00 HRH3 (0.33) HRH3MGLL
SCHEMBL15471693 1.00 HRH3 (0.33) HRH3MGLL
SCHEMBL13964214 1.00 HRH3 (0.33) HRH3MGLL
SCHEMBL20121264 1.00 HRH3 (0.33) HRH3MGLL
SCHEMBL22228552 0.96 HRH3 (0.32) HRH3MGLL
SCHEMBL13007041 0.96
SCHEMBL1074174 0.92
SCHEMBL22228574 0.89 TDP1 (0.35) MGLL
SCHEMBL230431 0.88

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023220129-A1 BENZOYPARAZINE PYRAZINES ANE THEIR USES FOGHORN THERAPEUTICS INC. (US) 2023-11-16 WO disclosed
US-20200337973-A1 FLUORESCENT DIRECT DYE BEARING AN ALIPHATIC CHAIN AND A DISULFIDE/THIOL/PROTECTED-THIOL FUNCTION FOR DYEING KERATIN MATERIALS L'OREAL (FR) 2020-10-29 US disclosed
EP-2677995-B1 COMPOSITION FOR DYEING KERATIN FIBRES COMPRISING A DIRECT DYE BEARING A DISULFIDE/THIOL FUNCTION, A NONIONIC SURFACTANT, AN AMPHOTERIC SURFACTANT, AN ALKALINE AGENT AND A REDUCING AGENT L'ORÉAL (FR) 2017-04-26 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200337973-A1 FLUORESCENT DIRECT DYE BEARING AN ALIPHATIC CHAIN AND A DISULFIDE/THIOL/PROTECTED-THIOL FUNCTION FOR DYEING KERATIN MATERIALS KRT18, TST, TUBA1C HRH3 2497/4885MGLL 4231/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.