Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 2/20 | 0.37 |
| ▸ | TRPM5 | Q9NZQ8 | 1/20 | 0.33 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.32 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.32 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.32 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.31 |
| ▸ | KDM4A | O75164 | 2/20 | 0.31 |
| ▸ | KDM2A | Q9Y2K7 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | GFER | P55789 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10104231 | 0.90 | GRM5 (0.44) | GRM5TRPM5PDE10ACYP11B1CYP11B2 | |
| SCHEMBL21005797 | 0.84 | GRM5 (0.42) | GRM5TRPM5PDE10ACYP11B1CYP11B2 | |
| SCHEMBL15460030 | 0.81 | GRM5 (0.37) | GRM5TRPM5CYP11B1CYP11B2PTGES2 | |
| SCHEMBL14392871 | 0.81 | GRM5 (0.44) | GRM5TRPM5PDE10ACYP11B1CYP11B2 | |
| SCHEMBL14392938 | 0.79 | GRM5 (0.38) | GRM5TRPM5PDE10ACYP11B1CYP11B2 | |
| SCHEMBL13695010 | 0.79 | GRM5 (0.35) | GRM5TRPM5 | |
| SCHEMBL19649341 | 0.78 | GRM5 (0.43) | GRM5TRPM5PDE10ACYP11B1CYP11B2 | |
| SCHEMBL10104188 | 0.74 | GRM5 (0.44) | GRM5TRPM5PDE10ACYP11B1CYP11B2 | |
| SCHEMBL10313124 | 0.72 | MEN1 (0.56) | KDM4AKDM2AMEN1NPC1APOBEC3A | |
| SCHEMBL15337731 | 0.71 | GRM5 (0.41) | GRM5TRPM5PDE10ACYP11B1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2677995-B1 | COMPOSITION FOR DYEING KERATIN FIBRES COMPRISING A DIRECT DYE BEARING A DISULFIDE/THIOL FUNCTION, A NONIONIC SURFACTANT, AN AMPHOTERIC SURFACTANT, AN ALKALINE AGENT AND A REDUCING AGENT | L'ORÉAL (FR) | 2017-04-26 | — | — | EP | disclosed |