Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 2/20 | 0.43 |
| ▸ | TRPM5 | Q9NZQ8 | 1/20 | 0.37 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.36 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | STAT3 | P40763 | 1/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MYC | P01106 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21005797 | 0.90 | GRM5 (0.42) | GRM5TRPM5CYP11B1CYP11B2L3MBTL1 | |
| SCHEMBL14392871 | 0.87 | GRM5 (0.44) | GRM5TRPM5CYP11B1CYP11B2L3MBTL1 | |
| SCHEMBL10104231 | 0.87 | GRM5 (0.44) | GRM5TRPM5CYP11B1CYP11B2L3MBTL1 | |
| SCHEMBL15460030 | 0.78 | GRM5 (0.37) | GRM5TRPM5CYP11B1CYP11B2L3MBTL1 | |
| SCHEMBL18774328 | 0.78 | GRM5 (0.37) | GRM5TRPM5CYP11B1CYP11B2L3MBTL1 | |
| SCHEMBL13695010 | 0.76 | GRM5 (0.35) | GRM5TRPM5 | |
| SCHEMBL13208462 | 0.75 | GRM5 (0.45) | GRM5TRPM5CYP11B1CYP11B2PTGES2 | |
| SCHEMBL10104188 | 0.73 | GRM5 (0.44) | GRM5TRPM5CYP11B1CYP11B2L3MBTL1 | |
| SCHEMBL5143030 | 0.73 | GRM5 (0.44) | GRM5TRPM5CYP11B1CYP11B2L3MBTL1 | |
| SCHEMBL5143029 | 0.73 | GRM5 (0.44) | GRM5TRPM5CYP11B1CYP11B2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2677996-B1 | COMPOSITION FOR DYEING KERATINOUS FIBRES COMPRISING A DIRECT DYE HAVING A DISULPHIDE/THIOL FUNCTIONAL GROUP, A THICKENING POLYMER, AN ETHOXYLATED FATTY ALCOHOL AND/OR A NONIONIC SURFACTANT, AN ALKALINE AGENT AND A REDUCING AGENT | L'ORÉAL (FR) | 2017-11-29 | — | — | EP | disclosed |