Sugi Predict

Sugi Predict / Compounds / SCHEMBL18778339

SCHEMBL18778339

SCHEMBL18778339

c1ccc(-c2nc3c4ccccc4c4ccccc4c3nc2-c2cccc(-c3ccc(-c4cccc(-c5ccc6c(c5)c5ccccc5n6-c5ccccc5)c4)cc3)c2)cc1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ L3MBTL1 Q9Y468 2/20 0.45
▸ KDM4E B2RXH2 1/20 0.45
▸ ATM Q13315 1/20 0.45
▸ NPY5R Q15761 1/20 0.39
▸ TSPO P30536 2/20 0.39
▸ PTGER4 P35408 1/20 0.37
▸ DHODH Q02127 1/20 0.35
▸ AVPR1A P37288 1/20 0.35
▸ KMT2A Q03164 3/20 0.34
▸ IL1R1 P14778 1/20 0.34
▸ HDAC4 P56524 1/20 0.34
▸ MEN1 O00255 2/20 0.33
▸ MAPT P10636 2/20 0.33
▸ ALDH1A1 P00352 1/20 0.33
▸ HTT P42858 1/20 0.33
▸ RXFP1 Q9HBX9 1/20 0.33
▸ ADORA2B P29275 1/20 0.33
▸ ADORA1 P30542 1/20 0.33
▸ MGAM O43451 1/20 0.32
▸ GAA P10253 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12268842 1.00 L3MBTL1 (0.45) L3MBTL1KDM4EATMNPY5RTSPO
SCHEMBL12268616 0.99 L3MBTL1 (0.46) L3MBTL1KDM4EATMNPY5RTSPO
SCHEMBL12268768 0.96 L3MBTL1 (0.49) L3MBTL1KDM4EATMNPY5RTSPO
SCHEMBL17464152 0.95 L3MBTL1 (0.45) L3MBTL1KDM4EATMNPY5RTSPO
SCHEMBL11950104 0.95 L3MBTL1 (0.45) L3MBTL1KDM4EATMNPY5RTSPO
SCHEMBL18778436 0.93 L3MBTL1 (0.45) L3MBTL1KDM4EATMDHODHAVPR1A
SCHEMBL18777887 0.92 ATM (0.44) L3MBTL1KDM4EATMNPY5RTSPO
SCHEMBL12013861 0.91 KDM4E (0.40) L3MBTL1KDM4EATMNPY5RTSPO
SCHEMBL18778145 0.91 NPY5R (0.41) L3MBTL1KDM4EATMNPY5RTSPO
SCHEMBL19655383 0.90 L3MBTL1 (0.45) L3MBTL1KDM4EATMNPY5RPTGER4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11522138-B2 Heterocyclic compound, light-emitting element, light-emitting device, electronic device, and lighting device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2022-12-06 — — US disclosed
US-20170117487-A1 Heterocyclic Compound, Light-Emitting Element, Light-Emitting Device, Electronic Device, and Lighting Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2017-04-27 — — US disclosed
US-20170117487-A1 Heterocyclic Compound, Light-Emitting Element, Light-Emitting Device, Electronic Device, and Lighting Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2017-04-27 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170117487-A1 Heterocyclic Compound, Light-Emitting Element, Light-Emitting Device, Electronic Device, and Lighting Device RECQL, HSF1, DDX41 L3MBTL1 1123/4885KDM4E 2319/4885ATM 1948/4885
US-11522138-B2 Heterocyclic compound, light-emitting element, light-emitting device, electronic device, and lighting device RECQL, HSF1, DDX41 L3MBTL1 1123/4885KDM4E 2319/4885ATM 1948/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.