SCHEMBL18779783

SCHEMBL18779783

CCCCCc1ccc(-c2ccc(-c3ccc(-c4ccc(CCC)c(F)c4F)c(F)c3)cc2)cc1

nearest known ligand 0.52

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
RARB P10826 10/20 0.52
RARA P10276 2/20 0.52
RARG P13631 1/20 0.52
TSHR P16473 1/20 0.40
HSD17B10 Q99714 1/20 0.40
MEN1 O00255 1/20 0.40
ALDH1A1 P00352 1/20 0.40
MAPT P10636 1/20 0.40
MTOR P42345 1/20 0.40
KMT2A Q03164 1/20 0.40
HTR2A P28223 1/20 0.40
CTSL P07711 1/20 0.38
CTSS P25774 1/20 0.38
CTSK P43235 1/20 0.38
HRH3 Q9Y5N1 1/20 0.38
LPL P06858 3/20 0.38
LIPG Q9Y5X9 3/20 0.38
MPL P40238 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19722146 1.00 RARB (0.52) RARBRARARARGTSHRHSD17B10
SCHEMBL18779779 0.96 RARB (0.47) RARBRARARARGTSHRHSD17B10
SCHEMBL15164264 0.95 RARB (0.55) RARBRARARARGTSHRHSD17B10
SCHEMBL18779776 0.92 RARB (0.55) RARBRARARARGTSHRHSD17B10
SCHEMBL18779777 0.92 CTSL (0.41) RARBRARARARGHSD17B10MAPT
SCHEMBL16377223 0.92 CTSL (0.41) RARBRARARARGHSD17B10MAPT
SCHEMBL18779782 0.91 RARB (0.54) RARBRARARARGTSHRHSD17B10
SCHEMBL16377229 0.88 CTSL (0.40) RARBRARARARGHSD17B10CTSL
SCHEMBL9496950 0.88 RARB (0.48) RARBRARARARGTSHRHSD17B10
SCHEMBL18779781 0.87 RARB (0.49) RARBRARARARGCTSLCTSS

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170226419-A1 POLYMERIZABLE-MONOMER-CONTAINING LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY ELEMENT USING SAME DIC CORPORATION (JP) 2017-08-10 US disclosed
EP-3159393-A1 POLYMERIZABLE-MONOMER-CONTAINING LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY ELEMENT USING SAME DIC Corporation (JP) 2017-04-26 EP disclosed