Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 3/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | RORC | P51449 | 14/20 | 0.37 |
| ▸ | F10 | P00742 | 1/20 | 0.36 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20802077 | 0.80 | F10 (0.54) | NAMPTF10 | |
| SCHEMBL18779773 | 0.77 | F10 (0.49) | F10 | |
| SCHEMBL31165348 | 0.69 | NPFFR1 (0.49) | NAMPTCA1 | |
| SCHEMBL18779770 | 0.67 | F10 (0.55) | F10 | |
| SCHEMBL8693590 | 0.66 | CA1 (0.54) | NAMPTCA1CA2PTPN11 | |
| SCHEMBL31165315 | 0.65 | NPFFR1 (0.46) | NAMPTRORC | |
| SCHEMBL29987151 | 0.65 | NAMPT (0.52) | NAMPTRORC | |
| SCHEMBL8117400 | 0.64 | TDP1 (0.42) | — | |
| SCHEMBL8692897 | 0.64 | CA1 (0.66) | NAMPTCA1CA2PTPN11 | |
| SCHEMBL5963740 | 0.64 | TDP1 (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2722330-B1 | NOVEL METHOD FOR SYNTHESIZING RIVAROXABAN INTERMEDIATE, 4-{4-[(5S)-5-(AMINOMETHYL)-2-OXO-1,3-OXAZOLIDIN-3-YL]PHENYL}MORPHOLIN-3-ONE | ZHEJIANG HUAHAI PHARM CO LTD (CN) | 2017-04-26 | — | — | EP | disclosed |