Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 3/20 | 0.52 |
| ▸ | PRKDC | P78527 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | CYP17A1 | P05093 | 2/20 | 0.44 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.43 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
| ▸ | LIPE | Q05469 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | RORC | P51449 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29986622 | 0.81 | PRKDC (0.49) | NAMPTPRKDCMAPTCYP17A1CD274 | |
| SCHEMBL993933 | 0.80 | GAA (0.64) | NAMPTMAPTDRD2SMN1; SMN2MEN1 | |
| SCHEMBL8346062 | 0.80 | PRKDC (0.63) | PRKDCMAPTCD274SMN1; SMN2TP53 | |
| SCHEMBL13055402 | 0.79 | CYP17A1 (0.59) | NAMPTCYP17A1PSMB8DRD2LIPE | |
| SCHEMBL23961145 | 0.79 | MAPT (0.48) | NAMPTPRKDCMAPTSMN1; SMN2TP53 | |
| SCHEMBL30817405 | 0.79 | MAPT (0.50) | NAMPTPRKDCMAPTCD274PSMB8 | |
| SCHEMBL6503210 | 0.79 | MAPT (0.50) | NAMPTPRKDCMAPTCD274SMN1; SMN2 | |
| SCHEMBL3573442 | 0.79 | GPR119 (0.50) | NAMPTPRKDCMAPTSMN1; SMN2GAA | |
| SCHEMBL3369741 | 0.78 | ALDH1A1 (0.55) | NAMPTPRKDCMAPTCD274DRD2 | |
| SCHEMBL30817330 | 0.78 | GPR119 (0.48) | NAMPTPRKDCMAPTCD274SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022251224-A1 | WEE1 INHIBITORS AND METHODS FOR TREATING CANCER | RECURIUM IP HOLDINGS, LLC (US) | 2022-12-01 | — | — | WO | disclosed |