SCHEMBL1878030

SCHEMBL1878030

O=C(C=Cc1ccccc1)c1ccc(O)c(O)c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SNCA P37840 3/20 0.83
XDH P47989 1/20 0.76
MAPT P10636 3/20 0.75
TERT O14746 1/20 0.75
CYP1B1 Q16678 6/20 0.67
MAOB P27338 2/20 0.67
HSPD1 P10809 2/20 0.67
HSPE1 P61604 2/20 0.67
MEN1 O00255 1/20 0.67
ALDH2 P05091 1/20 0.67
CYP3A4 P08684 1/20 0.67
CYP19A1 P11511 1/20 0.67
F3 P13726 1/20 0.67
MAOA P21397 1/20 0.67
KMT2A Q03164 1/20 0.67
TDP1 Q9NUW8 1/20 0.67
PLIN1 O60240 1/20 0.65
LMNA P02545 1/20 0.65
BCHE P06276 1/20 0.65
TNFRSF1A P19438 1/20 0.65

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10805975 1.00 SNCA (0.83) SNCAXDHMAPTTERTCYP1B1
SCHEMBL30736666 0.86 XDH (1.00) SNCAXDHMAPTTERTMAOB
SCHEMBL31436344 0.86 XDH (1.00) SNCAXDHMAPTTERTMAOB
SCHEMBL109015 0.86 SNCA (1.00) SNCAXDHMAPTTERT
SCHEMBL143710 0.86 SNCA (1.00) SNCAXDHMAPTTERT
SCHEMBL10165676 0.85 CYP1B1 (0.64) SNCAXDHMAPTCYP1B1MAOB
Hydrochloric Acid SCHEMBL10824571 0.84 CYP1B1 (0.62) SNCAXDHMAPTTERTCYP1B1
Hydrochloric Acid SCHEMBL10824570 0.84 CYP1B1 (0.62) SNCAXDHMAPTTERTCYP1B1
SCHEMBL28306876 0.83 GUSB (0.60) SNCAXDHMAPTCYP1B1MAOB
SCHEMBL16382589 0.83 CYP1B1 (0.58) SNCAXDHMAPTTERTCYP1B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7939674-B2 Process for producing an aromatic unsaturated compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-05-10 US disclosed
US-7700642-B2 Process for producing an aromatic unsaturated compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-04-20 US disclosed
US-20090111999-A1 PROCESS FOR PRODUCING AN AROMATIC UNSATURATED COMPOUND SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-04-30 US disclosed
US-20080221337-A1 Process for Producing an Aromatic Unsaturated Compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2008-09-11 US disclosed
EP-1666440-A1 METHOD FOR PRODUCING AROMATIC UNSATURATED COMPOUND Sumitomo Chemical Company, Limited (JP) 2006-06-07 EP disclosed
EP-0232679-B1 SYNTHETIC ORGANIC POLYMERS FOR THE SELECTIVE FLOCCULATION OF TITANIUM AND IRON ORES CONSIGLIO NAZIONALE DELLE RICERCHE (IT) 1990-07-25 EP disclosed
US-4698171-A Synthetic organic polymers for the selective flocculation of titanium and iron ores CONSIGLIO NAZIONALE DELLE RICERCHE (IT) 1987-10-06 US disclosed
EP-0232679-A1 Synthetic organic polymers for the selective flocculation of titanium and iron ores CONSIGLIO NAZIONALE DELLE RICERCHE (IT) 1987-08-19 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080221337-A1 Process for Producing an Aromatic Unsaturated Compound AHR, AR, ARSA SNCA 1797/4885XDH 322/4885MAPT 4307/4885
US-20090111999-A1 PROCESS FOR PRODUCING AN AROMATIC UNSATURATED COMPOUND AHR, AR, ARSA SNCA 1797/4885XDH 322/4885MAPT 4307/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.