Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 10/20 | 1.00 |
| ▸ | HSD11B2 | P80365 | 9/20 | 1.00 |
| ▸ | CES2 | O00748 | 5/20 | 1.00 |
| ▸ | CES1 | P23141 | 5/20 | 1.00 |
| ▸ | PTPN1 | P18031 | 3/20 | 1.00 |
| ▸ | CYP3A4 | P08684 | 2/20 | 1.00 |
| ▸ | MAPT | P10636 | 2/20 | 1.00 |
| ▸ | ALOX5 | P09917 | 2/20 | 1.00 |
| ▸ | MEN1 | O00255 | 1/20 | 1.00 |
| ▸ | AKR1B10 | O60218 | 1/20 | 1.00 |
| ▸ | LMNA | P02545 | 1/20 | 1.00 |
| ▸ | PRKCH | P24723 | 1/20 | 1.00 |
| ▸ | PTPN6 | P29350 | 1/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 1/20 | 1.00 |
| ▸ | PTPN11 | Q06124 | 1/20 | 1.00 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 1.00 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 1.00 |
| ▸ | TSHR | P16473 | 1/20 | 1.00 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.76 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.76 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Enoxolone SCHEMBL8896296 | 1.00 | HSD11B1 (1.00) | HSD11B1HSD11B2CES2CES1PTPN1 | |
| Enoxolone SCHEMBL19248152 | 1.00 | HSD11B1 (1.00) | HSD11B1HSD11B2CES2CES1PTPN1 | |
| Enoxolone SCHEMBL13144257 | 1.00 | HSD11B1 (1.00) | HSD11B1HSD11B2CES2CES1PTPN1 | |
| Enoxolone SCHEMBL23016683 | 1.00 | HSD11B1 (1.00) | HSD11B1HSD11B2CES2CES1PTPN1 | |
| Enoxolone SCHEMBL2762928 | 1.00 | HSD11B1 (1.00) | HSD11B1HSD11B2CES2CES1PTPN1 | |
| Enoxolone SCHEMBL23252837 | 1.00 | HSD11B1 (1.00) | HSD11B1HSD11B2CES2CES1PTPN1 | |
| Enoxolone SCHEMBL12444056 | 1.00 | HSD11B1 (1.00) | HSD11B1HSD11B2CES2CES1PTPN1 | |
| Enoxolone SCHEMBL14071726 | 1.00 | HSD11B1 (1.00) | HSD11B1HSD11B2CES2CES1PTPN1 | |
| Enoxolone SCHEMBL12225660 | 1.00 | HSD11B1 (1.00) | HSD11B1HSD11B2CES2CES1PTPN1 | |
| Enoxolone SCHEMBL14342758 | 1.00 | HSD11B1 (1.00) | HSD11B1HSD11B2CES2CES1PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8349309-B2 | Polymeric coupling agents and pharmaceutically-active polymers made therefrom | INTERFACE BIOLOGICS INC. (CA) | 2013-01-08 | — | — | US | disclosed |
| US-20110112259-A1 | POLYMERIC COUPLING AGENTS AND PHARMACEUTICALLY-ACTIVE POLYMERS MADE THEREFROM | INTERFACE BIOLOGICS, INC (CA) | 2011-05-12 | — | — | US | disclosed |