Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.59 |
| ▸ | TSHR | P16473 | 2/20 | 0.57 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | PPARD | Q03181 | 2/20 | 0.47 |
| ▸ | PTGDR2 | Q9Y5Y4 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | PPARG | P37231 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 2,4,5-Trichlorophenoxyacetic Acid SCHEMBL30445640 | 0.82 | TDP1 (0.65) | TDP1TSHRMCL1CYP2C19LMNA | |
| 2,4,5-Trichlorophenoxyacetic Acid SCHEMBL4864791 | 0.82 | TDP1 (0.65) | TDP1TSHRMCL1CYP2C19LMNA | |
| 2,4,5-Trichlorophenoxyacetic Acid SCHEMBL29525126 | 0.82 | TDP1 (0.65) | TDP1TSHRMCL1CYP2C19LMNA | |
| 2,4,5-Trichlorophenoxyacetic Acid SCHEMBL117704 | 0.82 | TDP1 (0.65) | TDP1TSHRMCL1CYP2C19LMNA | |
| SCHEMBL18780289 | 0.82 | KDM4E (0.49) | TDP1TSHRMCL1KDM4EALDH1A1 | |
| SCHEMBL16742711 | 0.82 | TDP1 (0.60) | TDP1TSHRMCL1CYP2C19LMNA | |
| 2,4,5-Trichlorophenoxyacetic Acid SCHEMBL10613998 | 0.81 | LMNA (0.64) | TDP1TSHRMCL1CYP2C19LMNA | |
| 2,4,5-Trichlorophenoxyacetic Acid SCHEMBL4586268 | 0.81 | TDP1 (0.62) | TDP1TSHRMCL1CYP2C19LMNA | |
| 2,4,5-Trichlorophenoxyacetic Acid SCHEMBL13571505 | 0.81 | TDP1 (0.62) | TDP1TSHRMCL1CYP2C19LMNA | |
| 2,4,5-Trichlorophenoxyacetic Acid SCHEMBL29484729 | 0.81 | TDP1 (0.62) | TDP1TSHRMCL1CYP2C19LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2308977-B2 | Novel herbicide resistance gene | DOW AGROSCIENCES LLC (US) | 2017-04-26 | — | — | EP | disclosed |