SCHEMBL18782878

SCHEMBL18782878

CCCCCCCCC(CCCCCCCC)OC=O

nearest known ligand 0.45

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ADH1B P00325 2/20 0.45
ADH1C P00326 2/20 0.45
ADH1A P07327 2/20 0.45
ADH4 P08319 2/20 0.45
ADH7 P40394 2/20 0.45
OPRM1 P35372 1/20 0.41
TSHR P16473 1/20 0.41
SMPD1 P17405 3/20 0.39
MAPT P10636 2/20 0.39
TRPA1 O75762 1/20 0.39
DDAH1 O94760 1/20 0.39
GAPDH P04406 1/20 0.39
GPR84 Q9NQS5 3/20 0.39
FDPS P14324 3/20 0.39
FFAR1 O14842 1/20 0.39
ZDHHC7 Q9NXF8 1/20 0.38
EPHX1 P07099 1/20 0.38
LMNA P02545 1/20 0.38
TP53 P04637 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20328385 1.00 ADH1B (0.45) ADH1BADH1CADH1AADH4ADH7
SCHEMBL17040070 1.00 ADH1B (0.45) ADH1BADH1CADH1AADH4ADH7
SCHEMBL25693415 1.00 ADH1B (0.45) ADH1BADH1CADH1AADH4ADH7
SCHEMBL18188028 1.00 ADH1B (0.45) ADH1BADH1CADH1AADH4ADH7
SCHEMBL1614822 1.00 ADH1B (0.45) ADH1BADH1CADH1AADH4ADH7
SCHEMBL24654117 1.00 ADH1B (0.45) ADH1BADH1CADH1AADH4ADH7
SCHEMBL17123651 1.00 ADH1B (0.45) ADH1BADH1CADH1AADH4ADH7
SCHEMBL17040069 1.00 ADH1B (0.45) ADH1BADH1CADH1AADH4ADH7
SCHEMBL25787303 1.00 ADH1B (0.45) ADH1BADH1CADH1AADH4ADH7
Ammonia Solution, Strong SCHEMBL28428879 0.98 ADH1B (0.44) ADH1BADH1CADH1AADH4ADH7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4310075-A2 IONIZABLE CATIONIC LIPID FOR RNA DELIVERY Arcturus Therapeutics, Inc. (US) 2024-01-24 EP disclosed
EP-3558943-B1 IONIZABLE CATIONIC LIPID FOR RNA DELIVERY ARCTURUS THERAPEUTICS INC (US) 2023-10-18 EP disclosed
EP-3736261-B1 COMPOUNDS AND COMPOSITIONS FOR INTRACELLULAR DELIVERY OF THERAPEUTIC AGENTS MODERNATX INC (US) 2023-10-11 EP disclosed
WO-2023144798-A1 IONIZABLE CATIONIC LIPIDS FOR LIPID NANOPARTICLES GENEVANT SCIENCES GMBH (CH) 2023-08-03 WO disclosed
WO-2023133089-A1 IONIZABLE LIPIDS FOR MULTIPLE ORGAN TARGETING MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2023-07-13 WO disclosed
EP-4137509-A1 COMBINATIONS OF MRNAS ENCODING IMMUNE MODULATING POLYPEPTIDES AND USES THEREOF ModernaTX, Inc. (US) 2023-02-22 EP disclosed
EP-3896164-A1 POLYNUCLEOTIDES ENCODING ALPHA-GALACTOSIDASE A FOR THE TREATMENT OF FABRY DISEASE ModernaTX, Inc. (US) 2021-10-20 EP disclosed
WO-2021055833-A1 BRANCHED TAIL LIPID COMPOUNDS AND COMPOSITIONS FOR INTRACELLULAR DELIVERY OF THERAPEUTIC AGENTS MODERNATX, INC. (US) 2021-03-25 WO disclosed
WO-2020257716-A1 TRICINE AND CITRIC ACID LIPIDS TRANSLATE BIO, INC. (US) 2020-12-24 WO disclosed
EP-3736261-A1 COMPOUNDS AND COMPOSITIONS FOR INTRACELLULAR DELIVERY OF THERAPEUTIC AGENTS ModernaTX, Inc. (US) 2020-11-11 EP disclosed
WO-2018075980-A1 HUMAN CYTOMEGALOVIRUS VACCINE MODERNATX, INC. (US) 2018-04-26 WO disclosed
WO-2017070616-A2 SEXUALLY TRANSMITTED DISEASE VACCINES MODERNATX, INC. (US) 2017-04-27 WO disclosed