Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 2/20 | 0.57 |
| ▸ | HPGD | P15428 | 11/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | PDE4A | P27815 | 1/20 | 0.49 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.49 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.49 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18783302 | 0.87 | GAA (0.57) | FGFR1HPGDALDH1A1PDE4APDE4B | |
| SCHEMBL18783301 | 0.83 | HPGD (0.61) | FGFR1HPGDALDH1A1PDE4APDE4B | |
| SCHEMBL17390036 | 0.79 | FASN (0.57) | FGFR1HPGDALDH1A1 | |
| SCHEMBL911484 | 0.77 | MGLL (0.57) | FGFR1HPGDALDH1A1HTT | |
| SCHEMBL911556 | 0.77 | MGLL (0.57) | FGFR1HPGDALDH1A1HTT | |
| SCHEMBL15154915 | 0.76 | HPGD (0.64) | FGFR1HPGDALDH1A1PDE4APDE4B | |
| SCHEMBL14686533 | 0.76 | HTT (0.64) | FGFR1HPGDALDH1A1PDE4APDE4B | |
| SCHEMBL21953471 | 0.75 | FGFR1 (0.54) | FGFR1HPGDALDH1A1PDE4APDE4B | |
| SCHEMBL1815887 | 0.75 | HPGD (0.64) | FGFR1HPGDPDE4APDE4BPDE4C | |
| SCHEMBL4941303 | 0.75 | HPGD (0.59) | FGFR1HPGDALDH1A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2976328-B1 | PIPERAZINE DERIVATIVES AS FASN INHIBITORS | MERCK PATENT GMBH (DE) | 2017-05-03 | — | — | EP | claimed |