Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.41 |
| ▸ | HTR6 | P50406 | 4/20 | 0.36 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | PLAU | P00749 | 1/20 | 0.35 |
| ▸ | NAT1 | P18440 | 1/20 | 0.34 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.31 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.30 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.30 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.30 |
| ▸ | BACE1 | P56817 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18784223 | 0.83 | CSNK2A1 (0.39) | CSNK2A1HTR6ALOX5APMAPTPLAU | |
| SCHEMBL14725681 | 0.80 | NAT1 (0.35) | ALOX5APPLAUNAT1PTGES2TSHR | |
| SCHEMBL18784244 | 0.79 | CSNK2A1 (0.40) | CSNK2A1HTR6ALOX5APMAPTPLAU | |
| SCHEMBL18784242 | 0.79 | CSNK2A1 (0.40) | CSNK2A1HTR6ALOX5APMAPTPLAU | |
| Hydrochloric Acid SCHEMBL1648037 | 0.79 | NAT1 (0.34) | CSNK2A1ALOX5APPLAUNAT1PTGES2 | |
| SCHEMBL6844903 | 0.74 | METAP2 (0.39) | ALOX5APPLAUNAT1PTGES2TSHR | |
| Hydrochloric Acid SCHEMBL1648362 | 0.73 | METAP2 (0.39) | CSNK2A1ALOX5APPLAUNAT1TSHR | |
| SCHEMBL18784224 | 0.72 | ALOX5AP (0.37) | ALOX5APMAPTNAT1PTGES2NPC1 | |
| SCHEMBL18784214 | 0.72 | CSNK2A1 (0.36) | CSNK2A1ALOX5APMAPTNAT1PTGES2 | |
| SCHEMBL1649388 | 0.72 | METAP2 (0.39) | ALOX5APPLAUNAT1PTGES2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2486004-B1 | SULPHONE COMPOUNDS FOR USE IN THE TREATMENT OF OBESITY | ZAFGEN INC (US) | 2017-05-03 | — | — | EP | claimed |