SCHEMBL1878428

SCHEMBL1878428

CCCCCCCCCCCCCCCCCCc1c2cccc1OOCC2

nearest known ligand 0.37

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
KCNH2 Q12809 2/20 0.37
CYP1A1 P04798 1/20 0.36
CYP2D6 P10635 2/20 0.34
ALDH1A1 P00352 1/20 0.33
CYP1A2 P05177 1/20 0.33
CYP2C19 P33261 1/20 0.33
DRD2 P14416 1/20 0.33
SLC6A2 P23975 1/20 0.33
HTR2A P28223 1/20 0.33
HTR2C P28335 1/20 0.33
SLC6A4 P31645 1/20 0.33
GPR84 Q9NQS5 1/20 0.33
CXCR5 P32302 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL498621 1.00 KCNH2 (0.37) KCNH2CYP1A1CYP2D6ALDH1A1CYP1A2
SCHEMBL28054371 1.00 KCNH2 (0.37) KCNH2CYP1A1CYP2D6ALDH1A1CYP1A2
SCHEMBL289726 1.00 KCNH2 (0.37) KCNH2CYP1A1CYP2D6ALDH1A1CYP1A2
SCHEMBL287633 1.00 KCNH2 (0.37) KCNH2CYP1A1CYP2D6ALDH1A1CYP1A2
SCHEMBL27995364 1.00 KCNH2 (0.37) KCNH2CYP1A1CYP2D6ALDH1A1CYP1A2
SCHEMBL28054351 1.00 KCNH2 (0.37) KCNH2CYP1A1CYP2D6ALDH1A1CYP1A2
SCHEMBL3262722 1.00 KCNH2 (0.37) KCNH2CYP1A1CYP2D6ALDH1A1CYP1A2
SCHEMBL7934680 1.00 KCNH2 (0.37) KCNH2CYP1A1CYP2D6ALDH1A1CYP1A2
Formaldehyde SCHEMBL8516632 0.96 CYP1A1 (0.37) KCNH2CYP1A1CYP2D6ALDH1A1CYP1A2
Acetic Acid SCHEMBL4544166 0.92 CXCR5 (0.38) KCNH2CYP1A1CXCR5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7939238-B2 Dry toner and method of preparing same RICOH COMPANY, LTD. (JP) 2011-05-10 US disclosed
EP-1347343-B1 Method of producing a toner RICOH KK (JP) 2009-08-19 EP disclosed
EP-1293839-B1 Dry toner RICOH KK (JP) 2009-07-22 EP disclosed
US-20090162780-A1 DRY TONER AND METHOD OF PREPARING SAME YAMASHITA HIROSHI 2009-06-25 US disclosed
EP-1205813-B1 Toner for dry developing RICOH KK (JP) 2008-10-22 EP disclosed
US-7419756-B2 Dry toner, method for manufacturing the same, image forming apparatus, and image forming method RICOH COMPANY, LTD. (JP) 2008-09-02 US disclosed
EP-1273977-B1 Dry toner and method of preparing same RICOH KK (JP) 2008-03-26 EP disclosed
US-7313353-B2 Fixing unit with heat-resisting resin base member and image forming toner for use in the fixing unit RICOH COMPANY, LTD. (JP) 2007-12-25 US disclosed
US-20070184370-A1 DRY TONER, METHOD FOR MANUFACTURING THE SAME, IMAGE FORMING APPARATUS, AND IMAGE FORMING METHOD YAMASHITA HIROSHI 2007-08-09 US disclosed
US-20070014603-A1 Fixing unit with heat-resisting resin base member and image forming toner for use in the fixing unit SATOH MASAHIKO 2007-01-18 US disclosed
US-20030113648-A1 Dry toner RICOH COMPANY, LTD. (JP) 2003-06-19 US disclosed
US-20030096185-A1 Dry toner, method for manufacturing the same, image forming apparatus, and image forming method RICOH COMPANY, LTD. (JP) 2003-05-22 US disclosed
US-20030055159-A1 Dry toner and method of preparing same RICOH COMPANY, LTD. (JP) 2003-03-20 US disclosed
EP-1293839-A2 Dry toner Ricoh Company, Ltd. (JP) 2003-03-19 EP disclosed
US-20030022084-A1 Dry toner and image forming method using same RICOH COMPANY, LTD. (JP) 2003-01-30 US disclosed
EP-1273977-A1 Dry toner and method of preparing same Ricoh Company, Ltd. (JP) 2003-01-08 EP disclosed
EP-1243976-A2 Dry toner and image forming method using same Ricoh Company, Ltd. (JP) 2002-09-25 EP disclosed
US-20020081510-A1 Toner for dry developing RICOH COMPANY, LTD. (JP) 2002-06-27 US disclosed
EP-1205813-A1 Toner for dry developing Ricoh Company, Ltd. (JP) 2002-05-15 EP disclosed
US-6140000-A TONERS OF RESINS WITH COLORS AND CHARGE CONTROL AGENTS RICOH COMPANY, LTD. (JP) 2000-10-31 US disclosed