Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 known ✓ | P11229 | 1/20 | 0.33 |
| ▸ | CHRM3 known ✓ | P20309 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 5/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | GRIN1 | Q05586 | 3/20 | 0.35 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | TSPO | P30536 | 2/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | HRH1 | P35367 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.33 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17378547 | 0.90 | ATM (0.43) | LMNAATMGRIN1GRIN2BTSPO | |
| SCHEMBL18784436 | 0.83 | LMNA (0.49) | LMNAKDM4ERAB9APOLBATM | |
| SCHEMBL18784615 | 0.80 | LMNA (0.55) | LMNAKDM4ERAB9APOLBSMN1; SMN2 | |
| SCHEMBL18784458 | 0.78 | LMNA (0.40) | LMNAKDM4ERAB9APOLBATM | |
| SCHEMBL18784573 | 0.77 | LMNA (0.58) | LMNAKDM4ERAB9APOLBSMN1; SMN2 | |
| SCHEMBL18784600 | 0.76 | LMNA (0.49) | LMNAKDM4ERAB9APOLBSMN1; SMN2 | |
| Dimethylformamide SCHEMBL18784393 | 0.75 | LMNA (0.51) | LMNAKDM4ERAB9APOLBSMN1; SMN2 | |
| SCHEMBL18784614 | 0.74 | LMNA (0.38) | LMNAKDM4ERAB9APOLBATM | |
| Trifluoromethanesulfonic Acid SCHEMBL18784542 | 0.73 | KCNH2 (0.41) | LMNAPOLBATMSMN1; SMN2KCNH2 | |
| SCHEMBL18784580 | 0.71 | LMNA (0.44) | LMNAKDM4ERAB9AATMSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3162799-B1 | FLUOROALKYLATING AGENT | KUMIAI CHEMICAL INDUSTRY CO (JP) | 2021-03-10 | — | — | EP | disclosed |
| US-20190233380-A1 | FLUOROALKYLATING AGENT | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 2019-08-01 | — | — | US | disclosed |
| US-10308613-B2 | Fluoroalkylating agent | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 2019-06-04 | — | — | US | disclosed |
| US-20170197920-A1 | FLUOROALKYLATING AGENT | IHARA CHEMICAL INDUSTRY CO., LTD. (JP) | 2017-07-13 | — | — | US | disclosed |
| EP-3162799-A1 | FLUOROALKYLATING AGENT | Ihara Chemical Industry Co., Ltd. (JP) | 2017-05-03 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10308613-B2 | Fluoroalkylating agent | AFF1, AFF4, AFF2 | CHRM1 113/4885CHRM3 631/4885LMNA 3147/4885 |
| US-20190233380-A1 | FLUOROALKYLATING AGENT | AFF1, AFF4, AFF2 | CHRM1 113/4885CHRM3 631/4885LMNA 3147/4885 |
| US-20170197920-A1 | FLUOROALKYLATING AGENT | AFF1, AFF4, AFF2 | CHRM1 113/4885CHRM3 631/4885LMNA 3147/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.