SCHEMBL187872

SCHEMBL187872

CS(=N)(=O)CC[C@H](N)C(=O)O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PMP22 Q01453 2/20 1.00
GCLC P48506 1/20 0.50
GSR P00390 2/20 0.46
GRM8 O00222 1/20 0.46
GRM6 O15303 1/20 0.46
GRIN2D O15399 1/20 0.46
GRIN3B O60391 1/20 0.46
CYP1A2 P05177 1/20 0.46
GRIK1 P39086 1/20 0.46
GRM5 P41594 1/20 0.46
GRIA1 P42261 1/20 0.46
GRIA2 P42262 1/20 0.46
GRIA3 P42263 1/20 0.46
SLC1A3 P43003 1/20 0.46
SLC1A2 P43004 1/20 0.46
SLC1A1 P43005 1/20 0.46
GRIA4 P48058 1/20 0.46
GRIN1 Q05586 1/20 0.46
GRIN2A Q12879 1/20 0.46
GRIK2 Q13002 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL187873 1.00 PMP22 (1.00) PMP22GCLCGSRGRM8GRM6
SCHEMBL8594079 1.00 PMP22 (1.00) PMP22GCLCGSRGRM8GRM6
SCHEMBL1347918 1.00 PMP22 (1.00) PMP22GCLCGSRGRM8GRM6
Ammonia Solution, Strong SCHEMBL16912221 0.98 PMP22 (0.96) PMP22GCLCGSRGRM8GRM6
Phosphoric Acid SCHEMBL4258425 0.92 PMP22 (0.85) PMP22GCLCGRM8GRM6GRM7
Glutamine SCHEMBL831562 0.89 PMP22 (0.79) PMP22GCLCGSRGRM8GRM6
SCHEMBL11582563 0.89 PMP22 (0.79) PMP22GCLCGSRGRM8GRM6
Methionine SCHEMBL8736510 0.88 PMP22 (0.77) PMP22GCLCGSRGRM8GRM6
Methionine Sulfoxide SCHEMBL829430 0.85 PMP22 (0.72) PMP22GCLCGSRGRM8GRM6
SCHEMBL10001779 0.83 PMP22 (0.70) PMP22GCLCNOS2SLC7A5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 5232 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4747627-A1 METHODS AND SYSTEMS FOR PREDICTIVE CLASSIFICATION BY MASS SPECTROMETRY AND TRAINED LARGE SPECTRAL MODELS Matterworks Inc (US) 2026-05-27 EP claimed
EP-4747275-A1 VECTORS INCORPORATING A COMBINATION OF PROMOTERS DRIVING SELECTABLE MARKER EXPRESSION Amgen Inc. (US) 2026-05-27 EP claimed
US-12570536-B2 Ammonia synthesis methods and systems PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2026-03-10 US claimed
EP-4655404-A1 GLUTAMINE SYNTHETASE MARKER FOR RECOMBINANT EXPRESSION Shanghai Zhenge Biotechnology Co., Ltd. (CN) 2025-12-03 EP claimed
US-20250332141-A1 A PHARMACEUTICAL COMPOSITION COMPRISING AN INHIBITOR OF GLUTAMINE SYNTHETASE ENZYME TO COMBAT ARTEMISININ RESISTANCE IN MALARIA INSTITUTE OF LIFE SCIENCES (IN) 2025-10-30 US claimed
WO-2025202830-A1 METHOD FOR ENHANCING PRODUCTIVITY OF CLONES EXPRESSING PEMBROLIZUMAB INTAS PHARMACEUTICALS LTD. (IN) 2025-10-02 WO claimed
US-20250129127-A1 Systems for Amplification of AAV Rep and Cap Proteins SHAPE THERAPEUTICS INC. 2025-04-24 US claimed
US-20250115666-A1 CELL CULTURE METHODS FOR PRODUCING THERAPEUTIC PROTEINS BRISTOL-MYERS SQUIBB COMPANY (US) 2025-04-10 US claimed
US-20250101402-A1 SELECTABLE MARKERS FOR EUKARYOTIC EXPRESSION SYSTEM SHANGHAI ZHENGE BIOTECHNOLOGY CO., LTD. (CN) 2025-03-27 US claimed
US-20250066491-A1 NOVEL MARKERS FOR RECOMBINANT PRODUCTION SYSTEM SHANGHAI ZHENGE BIOTECHNOLOGY CO., LTD. (CN) 2025-02-27 US claimed
US-5757408-A PRINTING IMAGE ON SUBSTRATE COATED WITH AMINO-ACID DERIVATIVE ADDITIVE; QUICK DRYING OF INK, OPTICAL DENSITY, NONCURLING XEROX CORPORATION (US) 1998-05-26 US claimed
EP-0824919-A2 Therapeutic methods and compositions for use therein Holt, John Alfred Gorton (AU) 1998-02-25 EP claimed
US-5683793-A Ink jet transparencies XEROX CORPORATION (US) 1997-11-04 US claimed
US-5589277-A INK JET PRINTING, AQUEOUS INKS, FAST DRYING XEROX CORPORATION (US) 1996-12-31 US claimed
US-5545819-A TRANSFORMED CELLS AND PLANTS NOT ONLY TOLERATE GLUTAMINE SYNTHETASE INHIBITORS BUT ARE EFFECTIVELY STIIMULATED BY SUCH HERBICIDES HOECHST AKTIENGESELLSCHAFT (DE) 1996-08-13 US claimed
EP-0531031-B1 Compositions for use in cancer therapy HOLT JOHN ALFRED GORTON (AU) 1995-11-02 EP claimed
EP-0667246-A1 Recording sheets containing amino acids, hydroxy acids, and polycarboxyl compounds XEROX CORPORATION (US) 1995-08-16 EP claimed
EP-0531031-A1 Compositions for use in cancer therapy Holt, John Alfred Gorton (AU) 1993-03-10 EP claimed
US-4659670-A Biological desulfurization of coal THE STANDARD OIL COMPANY 1987-04-21 US claimed
EP-0126443-A2 A process for the selective preparation of microorganisms capable of reproducible reduction of sulfur and use of the microorganism for microbial desulfurization of coal THE STANDARD OIL COMPANY (US) 1984-11-28 EP claimed