Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PMP22 | Q01453 | 2/20 | 0.72 |
| ▸ | GCLC | P48506 | 1/20 | 0.40 |
| ▸ | GRM4 | Q14833 | 2/20 | 0.35 |
| ▸ | GSR | P00390 | 2/20 | 0.35 |
| ▸ | GRM8 | O00222 | 1/20 | 0.35 |
| ▸ | GRM6 | O15303 | 1/20 | 0.35 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.35 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.35 |
| ▸ | GRM5 | P41594 | 1/20 | 0.35 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.35 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.35 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.35 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.35 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.35 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.35 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.35 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.35 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11582563 | 0.89 | PMP22 (0.79) | PMP22GCLCGRM4GSRGRM8 | |
| Methionine Sulfone SCHEMBL5955178 | 0.87 | PMP22 (0.51) | PMP22GCLCGRM4GSRGRM8 | |
| Methionine Sulfoxide SCHEMBL38627 | 0.85 | GSR (0.46) | PMP22GRM4GSRGRM8GRM6 | |
| SCHEMBL187873 | 0.85 | PMP22 (1.00) | PMP22GCLCGRM4GSRGRM8 | |
| Methionine Sulfoxide SCHEMBL38626 | 0.85 | GSR (0.46) | PMP22GRM4GSRGRM8GRM6 | |
| SCHEMBL1347918 | 0.85 | PMP22 (1.00) | PMP22GCLCGRM4GSRGRM8 | |
| Methionine Sulfoxide SCHEMBL689456 | 0.85 | GSR (0.46) | PMP22GRM4GSRGRM8GRM6 | |
| Methionine Sulfoxide SCHEMBL995666 | 0.85 | GSR (0.46) | PMP22GRM4GSRGRM8GRM6 | |
| Methionine Sulfoxide SCHEMBL4418369 | 0.85 | GSR (0.46) | PMP22GRM4GSRGRM8GRM6 | |
| Methionine Sulfoxide SCHEMBL689512 | 0.85 | GSR (0.46) | PMP22GRM4GSRGRM8GRM6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8143031-B2 | Production of N-acylated sulphur-containing amino acids with microorganisms having enhanced N-acyltransferase enzymatic activity | METABOLIC EXPLORER (FR) | 2012-03-27 | — | — | US | disclosed |
| EP-2331684-A1 | PRODUCTION OF N-ACYLATED SULPHUR-CONTAINING AMINO ACIDS WITH MICROORGANISMS HAVING ENHANCED N-ACYLTRANSFERASE ENZYMATIC ACTIVITY | Metabolic Explorer (FR) | 2011-06-15 | — | — | EP | disclosed |
| WO-2010020682-A1 | PRODUCTION OF N-ACYLATED SULPHUR-CONTAINING AMINO ACIDS WITH MICROORGANISMS HAVING ENHANCED N-ACYLTRANSFERASE ENZYMATIC ACTIVITY | METABOLIC EXPLORER (FR) | 2010-02-25 | — | — | WO | disclosed |
| WO-2010020289-A1 | PRODUCTION OF N-ACETYLATED SULPHUR-CONTAINING AMINO ACIDS WITH MICROORGANISMS HAVING ENHANCED N-ACETYLTRANSFERASE ENZYMATIC ACTIVITY | METABOLIC EXPLORER (FR) | 2010-02-25 | — | — | WO | disclosed |
| US-20100047880-A1 | PRODUCTION OF N-ACYLATED SULPHUR-CONTAINING AMINO ACIDS WITH MICROORGANISMS HAVING ENHANCED N-ACYLTRANSFERASE ENZYMATIC ACTIVITY | METABOLIC EXPLORER (FR) | 2010-02-25 | — | — | US | disclosed |