Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.72 |
| ▸ | S1PR2 | O95136 | 4/20 | 0.64 |
| ▸ | S1PR1 | P21453 | 4/20 | 0.64 |
| ▸ | S1PR3 | Q99500 | 4/20 | 0.64 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.58 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.58 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.56 |
| ▸ | PPARG | P37231 | 7/20 | 0.56 |
| ▸ | PPARD | Q03181 | 7/20 | 0.56 |
| ▸ | PPARA | Q07869 | 7/20 | 0.56 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.56 |
| ▸ | TSHR | P16473 | 4/20 | 0.56 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.56 |
| ▸ | TLR2 | O60603 | 2/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.56 |
| ▸ | FABP4 | P15090 | 2/20 | 0.56 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.56 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | ESR1 | P03372 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11423057 | 1.00 | ALDH1A1 (0.72) | ALDH1A1S1PR2S1PR1S1PR3FFAR4 | |
| SCHEMBL11629167 | 1.00 | ALDH1A1 (0.72) | ALDH1A1S1PR2S1PR1S1PR3FFAR4 | |
| SCHEMBL1880369 | 1.00 | ALDH1A1 (0.72) | ALDH1A1S1PR2S1PR1S1PR3FFAR4 | |
| SCHEMBL1873223 | 1.00 | ALDH1A1 (0.72) | ALDH1A1S1PR2S1PR1S1PR3FFAR4 | |
| SCHEMBL1879249 | 1.00 | ALDH1A1 (0.72) | ALDH1A1S1PR2S1PR1S1PR3FFAR4 | |
| SCHEMBL288296 | 1.00 | ALDH1A1 (0.72) | ALDH1A1S1PR2S1PR1S1PR3FFAR4 | |
| SCHEMBL1234410 | 1.00 | ALDH1A1 (0.72) | ALDH1A1S1PR2S1PR1S1PR3FFAR4 | |
| SCHEMBL11689168 | 1.00 | ALDH1A1 (0.72) | ALDH1A1S1PR2S1PR1S1PR3FFAR4 | |
| SCHEMBL11787433 | 0.98 | ALDH1A1 (0.70) | ALDH1A1S1PR2S1PR1S1PR3FFAR4 | |
| SCHEMBL8509937 | 0.98 | ALDH1A1 (0.69) | ALDH1A1S1PR2S1PR1S1PR3FFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110105417-A1 | Drug Conjugates | THE CURATORS OF THE UNIVERSITY OF MISSOURI | 2011-05-05 | — | — | US | disclosed |
| WO-2009158633-A1 | DRUG CONJUGATES | CURATORS OF THE UNIVERSITY OF MISSOURI ON BEHALF OF THE UNIVERSITY OF MISSOURI-KANSAS CITY (US) | 2009-12-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110105417-A1 | Drug Conjugates | ABCB1, SLCO2B1, ABCG2 | ALDH1A1 660/4885S1PR2 693/4885S1PR1 679/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.