Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BIRC2 | Q13490 | 4/20 | 0.48 |
| ▸ | TAS1R3 | Q7RTX0 | 5/20 | 0.43 |
| ▸ | TAS1R1 | Q7RTX1 | 5/20 | 0.43 |
| ▸ | MME | P08473 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20739435 | 0.83 | CA1 (0.35) | BIRC2TAS1R3TAS1R1MMEPOLB | |
| SCHEMBL18762523 | 0.83 | CTSL (0.53) | BIRC2 | |
| SCHEMBL18762521 | 0.83 | CTSL (0.53) | BIRC2 | |
| SCHEMBL18774994 | 0.82 | BIRC2 (0.48) | BIRC2TAS1R3TAS1R1MMEPOLB | |
| SCHEMBL18790951 | 0.82 | BIRC2 (0.48) | BIRC2TAS1R3TAS1R1MMEPOLB | |
| Hydrochloric Acid SCHEMBL18762561 | 0.81 | BIRC2 (0.47) | BIRC2TAS1R3TAS1R1MMEPOLB | |
| Hydrochloric Acid SCHEMBL18762558 | 0.81 | BIRC2 (0.47) | BIRC2TAS1R3TAS1R1MMEPOLB | |
| SCHEMBL4576576 | 0.80 | CTSL (0.56) | BIRC2 | |
| SCHEMBL14298966 | 0.79 | BIRC2 (0.54) | BIRC2TAS1R3TAS1R1MMEPOLB | |
| SCHEMBL14117890 | 0.79 | BIRC2 (0.54) | BIRC2TAS1R3TAS1R1MMEPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017070518-A1 | MODULATORS OF SESTRIN-GATOR2 INTERACTION AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2017-04-27 | — | — | WO | disclosed |