SCHEMBL187941

SCHEMBL187941

COc1ccc(Cn2cnnn2)cc1OC

nearest known ligand 0.76

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 4/20 0.76
MEN1 O00255 2/20 0.76
CYP1A2 P05177 1/20 0.76
CYP2C9 P11712 1/20 0.76
MAPK1 P28482 3/20 0.51
KDM4E B2RXH2 2/20 0.51
L3MBTL1 Q9Y468 1/20 0.51
LMNA P02545 1/20 0.49
SMN1; SMN2 Q16637 1/20 0.49
SIGMAR1 Q99720 1/20 0.49
CA2 P00918 1/20 0.49
TSHR P16473 3/20 0.45
ALDH1A1 P00352 3/20 0.45
PDE4B Q07343 1/20 0.44
ATM Q13315 1/20 0.44
HTR1A P08908 1/20 0.43
HTR2C P28335 1/20 0.43
HSP90AA1 P07900 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29788855 0.85 MEN1 (0.57) KMT2AMEN1CYP1A2CYP2C9KDM4E
SCHEMBL8647253 0.83 KMT2A (0.62) KMT2AMEN1CYP1A2CYP2C9MAPK1
SCHEMBL8534329 0.83 KMT2A (0.62) KMT2AMEN1CYP1A2CYP2C9MAPK1
SCHEMBL6997910 0.82 KMT2A (0.64) KMT2AMEN1CYP1A2CYP2C9MAPK1
SCHEMBL6998217 0.81 KMT2A (0.63) KMT2AMEN1CYP1A2CYP2C9MAPK1
SCHEMBL6998331 0.81 MEN1 (0.63) KMT2AMEN1CYP1A2CYP2C9MAPK1
SCHEMBL972345 0.79 MEN1 (0.60) KMT2AMEN1CYP1A2CYP2C9MAPK1
SCHEMBL29788845 0.73 KMT2A (0.54) KMT2AMEN1CYP1A2CYP2C9KDM4E
SCHEMBL10053477 0.73 MEN1 (0.53) KMT2AMEN1CYP1A2CYP2C9MAPK1
SCHEMBL5905876 0.72 MEN1 (0.52) KMT2AMEN1CYP1A2CYP2C9MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 197 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113646402-A Method for detecting and enumerating microorganisms 3M创新有限公司 2021-11-12 CN claimed
EP-2200562-B1 DENTAL COMPOSITION FOR DETECTING BACTERIA, KIT OF PARTS AND USE THEREOF 3M INNOVATIVE PROPERTIES CO (US) 2014-04-23 EP claimed
EP-1294922-B1 TREATING CANCER USING ORGANELLE CRYSTALLIZING AGENTS KONG QINGZHONG (CN) 2010-04-14 EP claimed
US-7524872-B2 Method and composition for treating cancer using cellular organelle crystallizing agents KONG QINGZHONG 2009-04-28 US claimed
US-20080166753-A1 Microbial Growth Assay UNIVERSITY TECHNOLOGIES INTERNATIONAL INC. (CA) 2008-07-10 US claimed
US-20060286170-A1 Method and composition for treating cancer using cellular organelle crystallizing agents KONG QINGZHONG 2006-12-21 US claimed
US-7102011-B2 Methods and compositions for the visualization of cellular organelles using tetrazolium salts KONG QINGZHONG 2006-09-05 US claimed
WO-2005098023-A1 MICROBIAL GROWTH ASSAY UNIVERSITY TECHNOLOGIES INTERNATIONAL INC. (CA) 2005-10-20 WO claimed
US-6864272-B2 Method and composition for treating cancer using cellular organelle crystallizing agents KONG QINGZHONG (US) 2005-03-08 US claimed
US-6703216-B2 AN OXIDIZED COFACTOR FOR THE FIRST OXIDOREDUCTASE THAT IS REDUCED UPON OXIDATION OF GHB BY THE FIRST OXIDOREDUCTASE IS IN TURN OXIDIZED BY ANOTHER OXIDOREDUCTASE CAUSING DETECTABLE CONVERSION OF CHROMOGEN OR DYE THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2004-03-09 US claimed
US-20020086345-A1 Methods and compositions for the visualization of cellular organelles using tetrazolium salts KONG QINGZHONG (US) 2002-07-04 US claimed
US-6376525-B1 Tetrazolium salts and derivatives, preferably tetrazolium red and tetrazolium violet, in combination with chemotherapeutic agents delivered in a polylactic acid carrier; noninvasive antitumor treatments KONG QINGZHONG (US) 2002-04-23 US claimed
US-6368818-B1 VISUAL AIDS AND CANCER TREATMENT KONG QINGZHONG (US) 2002-04-09 US claimed
WO-2001082780-A2 METHOD FOR TREATING CANCER, VISUALIZING CELL STRUCTURES, AND ISOLATING ORGANELLES USING ORGANELLE CRYSTALLIZING AGENTS KONG QINGZHONG (US) 2001-11-08 WO claimed
EP-0971037-A2 Stable reagent for formazan-based assay Kirkegaard & Perry Laboratories, Inc. (US) 2000-01-12 EP claimed
EP-0620844-B1 CULTURE MEDIA DEVICE MINNESOTA MINING & MFG (US) 1996-01-03 EP claimed
EP-0620844-A1 CULTURE MEDIA DEVICE. MINNESOTA MINING & MFG (US) 1994-10-26 EP claimed
US-5232838-A CULTURE MEDIA DEVICE AND METHOD OF USE MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1993-08-03 US claimed
WO-1993012218-A1 CULTURE MEDIA DEVICE MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1993-06-24 WO claimed
US-4892817-A INDOXYL PHOSPHATE, TETRAZOLIUM SALT, AND WATER SOLUBLE FERRICYANIDE FERROCYANIDE SALT BIOGENEX LABORATORIES (US) 1990-01-09 US claimed