Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.62 |
| ▸ | MEN1 | O00255 | 2/20 | 0.62 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.62 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL187941 | 0.83 | KMT2A (0.76) | KMT2AMEN1CYP1A2CYP2C9KDM4E | |
| SCHEMBL8534329 | 0.79 | KMT2A (0.62) | KMT2AMEN1CYP1A2CYP2C9KDM4E | |
| SCHEMBL6997910 | 0.78 | KMT2A (0.64) | KMT2AMEN1CYP1A2CYP2C9KDM4E | |
| SCHEMBL6998331 | 0.77 | MEN1 (0.63) | KMT2AMEN1CYP1A2CYP2C9KDM4E | |
| SCHEMBL6998217 | 0.77 | KMT2A (0.63) | KMT2AMEN1CYP1A2CYP2C9KDM4E | |
| SCHEMBL8594200 | 0.74 | ALDH1A1 (0.50) | KMT2AMEN1ALDH1A1TSHRLMNA | |
| SCHEMBL29788855 | 0.72 | MEN1 (0.57) | KMT2AMEN1CYP1A2CYP2C9KDM4E | |
| SCHEMBL972345 | 0.72 | MEN1 (0.60) | KMT2AMEN1CYP1A2CYP2C9KDM4E | |
| SCHEMBL10066409 | 0.68 | MEN1 (0.54) | KMT2AMEN1CYP1A2CYP2C9KDM4E | |
| SCHEMBL29788845 | 0.67 | KMT2A (0.54) | KMT2AMEN1CYP1A2CYP2C9KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0874843-A1 | NOVEL SUBSTITUTED 4-(1H-BENZIMIDAZOL-2-YL) 1,4]DIAZEPANES USEFUL FOR THE TREATMENT OF ALLERGIC DISEASES | HOECHST MARION ROUSSEL, INC. (US) | 1998-11-04 | — | — | EP | disclosed |
| WO-1997022604-A1 | NOVEL SUBSTITUTED 4-(1H-BENZIMIDAZOL-2-YL)[1,4]DIAZEPANES USEFUL FOR THE TREATMENT OF ALLERGIC DISEASES | HOECHST MARION ROUSSEL, INC. (US) | 1997-06-26 | — | — | WO | disclosed |