SCHEMBL1879478

SCHEMBL1879478

CCOP(C)(=O)C(C)C(=O)O

nearest known ligand 0.40

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.39
ALDH1A1 P00352 2/20 0.39
KDM4E B2RXH2 1/20 0.39
TP53 P04637 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
PPARD Q03181 2/20 0.35
POLB P06746 1/20 0.35
MAPT P10636 1/20 0.35
MAPK1 P28482 1/20 0.35
CA12 O43570 1/20 0.34
CA1 P00915 1/20 0.34
CA2 P00918 1/20 0.34
CA9 Q16790 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10293871 0.83 PPARD (0.40) TSHRALDH1A1KDM4ETP53TDP1
SCHEMBL4050 0.80 POLB (0.44) TSHRALDH1A1KDM4ETP53TDP1
SCHEMBL20364191 0.79 CA1 (0.36) TSHRALDH1A1KDM4ETP53TDP1
SCHEMBL3905072 0.78 PPARD (0.39) TSHRALDH1A1KDM4ETP53TDP1
SCHEMBL2983964 0.77 TSHR (0.39) TSHRALDH1A1KDM4ETP53TDP1
SCHEMBL22207787 0.77 TSHR (0.37) TSHRALDH1A1KDM4ETP53TDP1
SCHEMBL1107289 0.75
SCHEMBL1877202 0.75 TP53 (0.35) TP53CA12CA1CA2CA9
SCHEMBL1107313 0.74
SCHEMBL12594467 0.71 TSHR (0.40) TSHRTP53TDP1PPARDPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7939588-B2 Salt of carboxyethyl phosphinate ester and flame retardant thermoplastic resin composition containing the same CHEIL INDUSTRIES INC (KR) 2011-05-10 US disclosed
EP-1968989-A1 SALT OF CARBOXYETHYL PHOSPHINATE ESTER AND FLAME RETARDANT THERMOPLASTIC RESIN COMPOSITION CONTAINING THE SAME Cheil Industries Inc. (KR) 2008-09-17 EP disclosed
WO-2007078028-A1 SALT OF CARBOXYETHYL PHOSPHINATE ESTER AND FLAME RETARDANT THERMOPLASTIC RESIN COMPOSITION CONTAINING THE SAME CHEIL INDUSTRIES INC. (KR) 2007-07-12 WO disclosed
US-20070155872-A1 SALT OF CARBOXYETHYL PHOSPHINATE ESTER AND FLAME RETARDANT THERMOPLASTIC RESIN COMPOSITION CONTAINING THE SAME CHEIL INDUSTRIES, INC. (KR) 2007-07-05 US disclosed