SCHEMBL4050

SCHEMBL4050

CCOP(=O)(OCC)C(C)C(=O)O

nearest known ligand 0.44

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.44
GAA P10253 1/20 0.41
CYP3A4 P08684 1/20 0.41
CYP2C9 P11712 1/20 0.41
CYP2C19 P33261 1/20 0.41
TSHR P16473 3/20 0.40
SMN1; SMN2 Q16637 1/20 0.38
TP53 P04637 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
PPARD Q03181 1/20 0.37
KDM4E B2RXH2 1/20 0.37
ALDH1A1 P00352 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL319717 0.82 TSHR (0.42) POLBGAACYP3A4CYP2C9CYP2C19
SCHEMBL3905072 0.80 PPARD (0.39) TSHRTP53TDP1PPARDKDM4E
SCHEMBL8199890 0.80 GAA (0.44) POLBGAACYP3A4CYP2C9CYP2C19
SCHEMBL1879478 0.80 TSHR (0.39) POLBTSHRTP53TDP1PPARD
SCHEMBL5839781 0.80 GAA (0.40) POLBGAACYP3A4CYP2C9CYP2C19
SCHEMBL10108 0.80 GAA (0.40) POLBGAACYP3A4CYP2C9CYP2C19
SCHEMBL9445952 0.80 GAA (0.40) POLBGAACYP3A4CYP2C9CYP2C19
SCHEMBL9445956 0.80 POLB (0.43) POLBGAACYP3A4CYP2C9CYP2C19
SCHEMBL31267383 0.79 GAA (0.36) POLBGAACYP3A4CYP2C9CYP2C19
SCHEMBL17937995 0.79 POLB (0.46) POLBGAACYP3A4CYP2C9CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 120 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2882030-B1 NON-AQUEOUS ELECTROLYTE AND ENERGY STORAGE DEVICE USING THE SAME UBE INDUSTRIES (JP) 2017-06-21 EP claimed
CN-103819484-B Synthesis method for natural jolkinolide A and B 中国药科大学 2017-04-19 CN claimed
CN-103819484-A Synthesis method for natural jolkinolide A and B UNIV CHINA PHARMA 2014-05-28 CN claimed
CN-102653543-A Preparation method, biological activity and application of 3-substituted type Jolkinolide compound UNIV CHINA PHARMA 2012-09-05 CN claimed
CN-102558288-A Preparation method of jolkinolide compound and application thereof UNIV CHINA PHARMA 2012-07-11 CN claimed
EP-1554330-B1 PARTIALLY ESTER-EXCHANGED SIPM AND PROCESS THEREWITH INVISTA TECH SARL (CH) 2009-03-11 EP claimed
EP-1615934-B1 TITANIUM CHELATE DISPERSIONS DU PONT (US) 2007-06-27 EP claimed
EP-1001951-B1 THIAZOLE DERIVATIVES, METHOD FOR THEIR PRODUCTION AND USE SCHERING AG (DE) 2002-09-25 EP claimed
JP-2000500758-A 2000-01-25 JP claimed
EP-0862575-A1 NOVEL GERANYLGERANYL-DERIVATIVES, PROCESS FOR THE PREPARATION THEREOF AND RELATED PHARMACEUTICAL COMPOSITIONS LABORATORI BALDACCI Spa (IT) 1998-09-09 EP claimed
WO-1997019091-A1 NOVEL GERANYLGERANYL-DERIVATIVES, PROCESS FOR THE PREPARATION THEREOF AND RELATED PHARMACEUTICAL COMPOSITIONS LABORATORI BALDACCI S.P.A. (IT) 1997-05-29 WO claimed
US-12630528-B2 Amino aryl derivative useful as diacylglycerol acyltransferase 2 inhibitor and use thereof LG CHEM, LTD. (KR) 2026-05-19 US disclosed
EP-4634167-A1 SUBSTITUTED PYRIDINES FOR USE IN TREATING OR PREVENTING INFLAMMATORY DISEASES OR DISEASES ASSOCIATED WITH AN UNDESIRABLE IMMUNE RESPONSE Sitryx Therapeutics Limited (GB) 2025-10-22 EP disclosed
US-20250270224-A1 POLYCYCLIC POLY(ADP-RIBOSE) POLYMERASE SELECTIVE INHIBITOR Xuanzhu Biopharmaceutical Co., Ltd. (CN) 2025-08-28 US disclosed
CN-120092010-A Polycyclic poly (ADP-ribose) polymerase selective inhibitors 轩竹生物科技股份有限公司 2025-06-03 CN disclosed
US-4307232-A Preparation of dialkyl- and diarylphosphonoalkanoic acids and substituted acrylic acids E. I. DU PONT DE NEMOURS AND COMPANY (US) 1981-12-22 US disclosed
US-4265769-A CORROSION RESISTANCE, ANTISCALING AGENTS CIBA-GEIGY CORPORATION (US) 1981-05-05 US disclosed
US-4208344-A CORROSION RESISTANCE, ANTISCALING AGENTS CIBA-GEIGY CORPORATION (US) 1980-06-17 US disclosed
US-3935271-A INSECTICIDE SANDOZ LTD. (CH) 1976-01-27 US disclosed
US-3932483-A INSECTICIDES SANDOZ LTD., (SANDOZ AG) (CH) 1976-01-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250270224-A1 POLYCYCLIC POLY(ADP-RIBOSE) POLYMERASE SELECTIVE INHIBITOR PARP1, PARP11, PARP2 POLB 31/4885GAA 274/4885CYP3A4 1409/4885
US-12630528-B2 Amino aryl derivative useful as diacylglycerol acyltransferase 2 inhibitor and use thereof DGAT2, DGAT1, SOAT2 POLB 3837/4885GAA 791/4885CYP3A4 1556/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.