Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 3/20 | 0.39 |
| ▸ | CA4 | P22748 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | MME | P08473 | 3/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.32 |
| ▸ | RIMKLA | Q8IXN7 | 1/20 | 0.32 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.32 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.32 |
| ▸ | GNPAT | O15228 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18794825 | 1.00 | CA2 (0.39) | CA2CA4TDP1SMN1; SMN2MME | |
| SCHEMBL17616069 | 1.00 | CA2 (0.39) | CA2CA4TDP1SMN1; SMN2MME | |
| SCHEMBL20521 | 0.91 | CA2 (0.44) | CA2CA4TDP1SMN1; SMN2MME | |
| SCHEMBL472192 | 0.91 | CA2 (0.44) | CA2CA4TDP1SMN1; SMN2MME | |
| SCHEMBL10801439 | 0.89 | CA2 (0.42) | CA2CA4TDP1SMN1; SMN2MME | |
| SCHEMBL10801445 | 0.89 | CA2 (0.42) | CA2CA4TDP1SMN1; SMN2MME | |
| SCHEMBL28372032 | 0.89 | CA2 (0.42) | CA2CA4TDP1SMN1; SMN2MME | |
| SCHEMBL28623751 | 0.89 | CA2 (0.42) | CA2CA4TDP1SMN1; SMN2MME | |
| SCHEMBL28623754 | 0.89 | CA2 (0.42) | CA2CA4TDP1SMN1; SMN2MME | |
| Phosphine SCHEMBL27579074 | 0.89 | CA2 (0.42) | CA2CA4TDP1SMN1; SMN2MME |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017070794-A1 | PROCESS FOR THE PREPARATION OF 2-[2-(2-AMINO-2-CARBOXY-ETHYLAMINO)-2-CARBOXY-ETHYLAMINO]-SUCCINIC ACID (AM-A) AND ANALOGS AND DERIVATIVES THEREOF | MCMASTER UNIVERSITY (CA) | 2017-05-04 | — | — | WO | disclosed |
| WO-2017070794-A1 | PROCESS FOR THE PREPARATION OF 2-[2-(2-AMINO-2-CARBOXY-ETHYLAMINO)-2-CARBOXY-ETHYLAMINO]-SUCCINIC ACID (AM-A) AND ANALOGS AND DERIVATIVES THEREOF | MCMASTER UNIVERSITY (CA) | 2017-05-04 | — | — | WO | disclosed |