SCHEMBL18794856

SCHEMBL18794856

O=C1OCC(CC(O)O)OC(=O)c2ccc1cc2

nearest known ligand 0.33

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
HTT P42858 1/20 0.33
CYP1A2 P05177 1/20 0.32
CYP2D6 P10635 1/20 0.32
CYP2C9 P11712 1/20 0.32
CYP2C19 P33261 1/20 0.32
AIMP2 Q13155 1/20 0.32
MTNR1A P48039 1/20 0.31
ALOX5 P09917 1/20 0.31
HPGD P15428 2/20 0.30
NPC1 O15118 1/20 0.30
RAB9A P51151 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30
ALDH1A1 P00352 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2479036 0.77 MAOA (0.40) HTTCYP1A2CYP2D6CYP2C9CYP2C19
SCHEMBL15014241 0.72 GRM2 (0.44) CYP1A2
SCHEMBL787167 0.71 PTPRF (0.30)
SCHEMBL66015 0.71 MAOA (0.37) SMN1; SMN2
SCHEMBL4168935 0.69 GRM2 (0.37) SMN1; SMN2
Ethylene SCHEMBL11664467 0.68 MAOA (0.35) SMN1; SMN2
Succinic Acid SCHEMBL1325312 0.68 HTT (0.40) HTTCYP1A2HPGDRAB9ASMN1; SMN2
SCHEMBL19025075 0.67 PTGS1 (0.30)
Adipic Acid SCHEMBL1326117 0.66 HTT (0.38) HTTSMN1; SMN2
SCHEMBL28475516 0.66

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2017070762-A1 PROCESS OF POLYPROPYLENE AND POLYETHYLENE DEPOLYMERIZATION THROUGH CHEMICAL RECYCLING VALE S.A. (BR) 2017-05-04 WO disclosed