Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IL1RN | P18510 | 2/20 | 0.49 |
| ▸ | ERAP2 | Q6P179 | 2/20 | 0.49 |
| ▸ | ERAP1 | Q9NZ08 | 2/20 | 0.49 |
| ▸ | GID4 | Q8IVV7 | 1/20 | 0.45 |
| ▸ | ACHE | P22303 | 2/20 | 0.44 |
| ▸ | ANPEP | P15144 | 2/20 | 0.42 |
| ▸ | KDM1A | O60341 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | DRD1 | P21728 | 1/20 | 0.36 |
| ▸ | DRD4 | P21917 | 1/20 | 0.36 |
| ▸ | DRD5 | P21918 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | HTR2B | P41595 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1150600 | 1.00 | IL1RN (0.49) | IL1RNERAP2ERAP1GID4ACHE | |
| SCHEMBL12402720 | 1.00 | IL1RN (0.49) | IL1RNERAP2ERAP1GID4ACHE | |
| Hydrochloric Acid SCHEMBL2167605 | 0.98 | IL1RN (0.47) | IL1RNERAP2ERAP1GID4ACHE | |
| Hydrochloric Acid SCHEMBL29984305 | 0.98 | IL1RN (0.47) | IL1RNERAP2ERAP1GID4ACHE | |
| Hydrochloric Acid SCHEMBL2167296 | 0.98 | IL1RN (0.47) | IL1RNERAP2ERAP1GID4ACHE | |
| Hydrochloric Acid SCHEMBL23355920 | 0.98 | IL1RN (0.47) | IL1RNERAP2ERAP1GID4ACHE | |
| SCHEMBL17193124 | 0.89 | GID4 (0.42) | IL1RNERAP2ERAP1GID4ACHE | |
| SCHEMBL29983834 | 0.89 | GID4 (0.42) | IL1RNERAP2ERAP1GID4ACHE | |
| SCHEMBL4019181 | 0.89 | GID4 (0.42) | IL1RNERAP2ERAP1GID4ACHE | |
| SCHEMBL4206687 | 0.89 | GID4 (0.42) | IL1RNERAP2ERAP1GID4ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4685149-A1 | NOVEL COMPOUND AS ENDOTHELIAL TO MESENCHYMAL TRANSITION (ENDMT) INHIBITOR, AND PHARMACEUTICAL COMPOSITION COMPRISING SAME | Korea Institute of Radiological & Medical Sciences (KR) | 2026-01-28 | — | — | EP | disclosed |
| WO-2024196236-A1 | NOVEL COMPOUND AS ENDOTHELIAL TO MESENCHYMAL TRANSITION (ENDMT) INHIBITOR, AND PHARMACEUTICAL COMPOSITION COMPRISING SAME | 주식회사 넥스트젠바이오사이언스 | 2024-09-26 | — | — | WO | disclosed |
| WO-2012158550-A9 | SELECTIVE HETEROCYCLIC SPHINGOSINE 1 PHOSPHATE RECEPTOR MODULATORS | RECEPTOS, INC. (US) | 2017-10-26 | — | — | WO | disclosed |
| EP-2844643-B1 | PYRIMIDINEDIONE CARBOXAMIDE INHIBITORS OF ENDOTHELIAL LIPASE | BRISTOL MYERS SQUIBB CO (US) | 2016-11-30 | — | — | EP | disclosed |
| US-9481659-B2 | Selective heterocyclic sphingosine 1 phosphate receptor modulators | CELGENE INTERNATIONAL II SÀRL (CH) | 2016-11-01 | — | — | US | disclosed |
| US-9481659-B2 | Selective heterocyclic sphingosine 1 phosphate receptor modulators | CELGENE INTERNATIONAL II SÀRL (CH) | 2016-11-01 | — | — | US | disclosed |
| CN-102724880-B | Sphingosine-1-phosphate receptor modulators and chiral synthesis methods | 瑞塞普托斯有限责任公司 | 2016-09-14 | — | — | CN | disclosed |
| US-9394264-B2 | Sphingosine 1 phosphate receptor modulators and methods of chiral synthesis | RECEPTOS, INC. (US) | 2016-07-19 | — | — | US | disclosed |
| US-9394264-B2 | Sphingosine 1 phosphate receptor modulators and methods of chiral synthesis | RECEPTOS, INC. (US) | 2016-07-19 | — | — | US | disclosed |
| US-9394264-B2 | Sphingosine 1 phosphate receptor modulators and methods of chiral synthesis | RECEPTOS, INC. (US) | 2016-07-19 | — | — | US | disclosed |
| US-8357706-B2 | Sphingosine 1 phosphate receptor modulators and methods of chiral synthesis | RECEPTOS, INC. (US) | 2013-01-22 | — | — | US | disclosed |
| CN-102753022-A | Selective heterocyclic sphingosine 1-phosphate receptor modulators | RECEPTOS INC | 2012-10-24 | — | — | CN | disclosed |
| EP-2498611-A1 | SPHINGOSINE 1 PHOSPHATE RECEPTOR MODULATORS AND METHODS OF CHIRAL SYNTHESIS | Receptos, Inc. (US) | 2012-09-19 | — | — | EP | disclosed |
| US-20110183953-A1 | SELECTIVE HETEROCYCLIC SPHINGOSINE 1 PHOSPHATE RECEPTOR MODULATORS | RECEPTOS LLC | 2011-07-28 | — | — | US | disclosed |
| US-20110183953-A1 | SELECTIVE HETEROCYCLIC SPHINGOSINE 1 PHOSPHATE RECEPTOR MODULATORS | RECEPTOS LLC | 2011-07-28 | — | — | US | disclosed |
| US-20110178056-A1 | SPHINGOSINE 1 PHOSPHATE RECEPTOR MODULATORS AND METHODS OF CHIRAL SYNTHESIS | RECEPTOS LLC | 2011-07-21 | — | — | US | disclosed |
| US-20110178056-A1 | SPHINGOSINE 1 PHOSPHATE RECEPTOR MODULATORS AND METHODS OF CHIRAL SYNTHESIS | RECEPTOS LLC | 2011-07-21 | — | — | US | disclosed |
| US-20110178056-A1 | SPHINGOSINE 1 PHOSPHATE RECEPTOR MODULATORS AND METHODS OF CHIRAL SYNTHESIS | RECEPTOS LLC | 2011-07-21 | — | — | US | disclosed |
| WO-2011060389-A1 | SPHINGOSINE 1 PHOSPHATE RECEPTOR MODULATORS AND METHODS OF CHIRAL SYNTHESIS | RECEPTOS, INC. (US) | 2011-05-19 | — | — | WO | disclosed |
| WO-2011060389-A1 | SPHINGOSINE 1 PHOSPHATE RECEPTOR MODULATORS AND METHODS OF CHIRAL SYNTHESIS | RECEPTOS, INC. (US) | 2011-05-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110178056-A1 | SPHINGOSINE 1 PHOSPHATE RECEPTOR MODULATORS AND METHODS OF CHIRAL SYNTHESIS | S1PR1, S1PR3, S1PR2 | IL1RN 394/4885ERAP2 1967/4885ERAP1 1773/4885 |
| US-20110183953-A1 | SELECTIVE HETEROCYCLIC SPHINGOSINE 1 PHOSPHATE RECEPTOR MODULATORS | S1PR1, S1PR3, S1PR2 | IL1RN 334/4885ERAP2 2011/4885ERAP1 1932/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.