Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 6/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | ERN1 | O75460 | 1/20 | 0.33 |
| ▸ | PTGER3 | P43115 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.32 |
| ▸ | CTSL | P07711 | 1/20 | 0.32 |
| ▸ | CTSS | P25774 | 1/20 | 0.32 |
| ▸ | CTSK | P43235 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.30 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.30 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18796121 | 0.87 | MAP4K4 (0.37) | HTTKMT2AL3MBTL1MEN1ALDH1A1 | |
| SCHEMBL18796276 | 0.80 | HTT (0.40) | HTTKMT2AL3MBTL1MEN1ALDH1A1 | |
| SCHEMBL20551281 | 0.78 | HTT (0.36) | HTTKMT2AL3MBTL1MEN1ALDH1A1 | |
| SCHEMBL20552215 | 0.76 | HTT (0.31) | HTTKMT2AL3MBTL1MEN1ALDH1A1 | |
| SCHEMBL18795982 | 0.69 | MAP4K4 (0.32) | MAP4K4 | |
| SCHEMBL18796156 | 0.68 | SLC22A12 (0.31) | — | |
| SCHEMBL18796129 | 0.68 | HTT (0.57) | HTTKMT2AL3MBTL1MEN1ALDH1A1 | |
| SCHEMBL21858405 | 0.67 | HTT (0.60) | HTTKMT2AL3MBTL1MEN1ALDH1A1 | |
| SCHEMBL30829782 | 0.65 | ERN1 (0.42) | KMT2AMEN1ALDH1A1ERN1LMNA | |
| SCHEMBL6557478 | 0.65 | ERN1 (0.42) | KMT2AMEN1ALDH1A1ERN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108349897-B | Trisubstituted silylphenoxyheterocycles and analogs | 拜耳作物科学股份公司 | 2022-03-04 | — | — | CN | disclosed |
| EP-3368514-B1 | TRISUBSTITUTED SILYLPHENOXYHETEROCYCLES AND ANALOGUES | BAYER CROPSCIENCE AG (DE) | 2021-08-18 | — | — | EP | disclosed |
| EP-3368514-B1 | TRISUBSTITUTED SILYLPHENOXYHETEROCYCLES AND ANALOGUES | BAYER CROPSCIENCE AG (DE) | 2021-08-18 | — | — | EP | disclosed |
| US-10683311-B2 | Trisubstitutedsilylphenoxyheterocycles and analogues | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2020-06-16 | — | — | US | disclosed |
| US-10683311-B2 | Trisubstitutedsilylphenoxyheterocycles and analogues | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2020-06-16 | — | — | US | disclosed |
| US-20190233444-A1 | TRISUBSTITUTEDSILYLPHENOXYHETEROCYCLES AND ANALOGUES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2019-08-01 | — | — | US | disclosed |
| US-20190233444-A1 | TRISUBSTITUTEDSILYLPHENOXYHETEROCYCLES AND ANALOGUES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2019-08-01 | — | — | US | disclosed |
| EP-3368514-A1 | TRISUBSTITUTEDSILYLPHENOXYHETEROCYCLES AND ANALOGUES | Bayer CropScience Aktiengesellschaft (DE) | 2018-09-05 | — | — | EP | disclosed |
| WO-2017072283-A1 | TRISUBSTITUTEDSILYLPHENOXYHETEROCYCLES AND ANALOGUES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2017-05-04 | — | — | WO | disclosed |
| WO-2017072283-A1 | TRISUBSTITUTEDSILYLPHENOXYHETEROCYCLES AND ANALOGUES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2017-05-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10683311-B2 | Trisubstitutedsilylphenoxyheterocycles and analogues | PIK3C3, ERG28, DDT | HTT 3740/4885KMT2A 1780/4885L3MBTL1 2453/4885 |
| US-20190233444-A1 | TRISUBSTITUTEDSILYLPHENOXYHETEROCYCLES AND ANALOGUES | PIK3C3, ERG28, DDT | HTT 3740/4885KMT2A 1780/4885L3MBTL1 2453/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.