SCHEMBL18796261

SCHEMBL18796261

CC=CCOP(=O)(OCO)OP(=O)(O)O

nearest known ligand 0.38

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
BTN3A1 O00481 6/20 0.38
FNTA P49354 9/20 0.33
FNTB P49356 7/20 0.33
PGGT1B P53609 3/20 0.33
FDPS P14324 1/20 0.31
BLM P54132 1/20 0.31
TDP1 Q9NUW8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28690269 0.86 BTN3A1 (0.36) BTN3A1FNTAFNTBPGGT1B
SCHEMBL2594778 0.80 TSHR (0.32)
SCHEMBL23013402 0.78 BTN3A1 (0.43) BTN3A1FNTAFNTBPGGT1B
SCHEMBL18796260 0.78 BTN3A1 (0.43) BTN3A1FNTAFNTBPGGT1B
Crotyl Pyrophosphate SCHEMBL2513892 0.77 BTN3A1 (0.60) BTN3A1FNTAFNTBPGGT1B
Crotyl Pyrophosphate SCHEMBL14993578 0.77 BTN3A1 (0.60) BTN3A1FNTAFNTBPGGT1B
SCHEMBL1506680 0.76
SCHEMBL13268920 0.76
SCHEMBL6537391 0.76 TSHR (0.41)
SCHEMBL6537388 0.76 TSHR (0.41)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 51 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12637659-B2 Expansion of non-haematopoietic tissue-resident gamma delta T cells and uses of these cells CANCER RESEARCH TECHNOLOGY LIMITED (GB) 2026-05-26 US disclosed
EP-4010082-B9 MULTISPECIFIC ANTI-TCR DELTA VARIABLE 1 ANTIBODIES GAMMADELTA THERAPEUTICS LTD (GB) 2026-03-04 EP disclosed
US-12458698-B2 Expansion of γδ T cells, compositions, and methods of use thereof KING'S COLLEGE LONDON (GB) 2025-11-04 US disclosed
US-12312408-B2 Multispecific anti-TCR delta variable 1 antibodies GAMMADELTA THERAPEUTICS LTD (GB) 2025-05-27 US disclosed
US-20240376215-A1 MULTISPECIFIC ANTI-TCR DELTA VARIABLE 1 ANTIBODIES GAMMADELTA THERAPEUTICS LTD (GB) 2024-11-14 US disclosed
EP-4265642-B1 MULTISPECIFIC ANTI-TCR DELTA VARIABLE 1 ANTIBODIES GAMMADELTA THERAPEUTICS LTD (GB) 2024-06-26 EP disclosed
EP-4269444-B1 MULTISPECIFIC ANTI-TCR DELTA VARIABLE 1 ANTIBODIES GAMMADELTA THERAPEUTICS LTD (GB) 2024-06-26 EP disclosed
EP-4265643-B1 MULTISPECIFIC ANTI-TCR DELTA VARIABLE 1 ANTIBODIES GAMMADELTA THERAPEUTICS LTD (GB) 2024-06-26 EP disclosed
EP-4269446-B1 MULTISPECIFIC ANTI-TCR DELTA VARIABLE 1 ANTIBODIES GAMMADELTA THERAPEUTICS LTD (GB) 2024-06-26 EP disclosed
EP-4269445-B1 MULTISPECIFIC ANTI-TCR DELTA VARIABLE 1 ANTIBODIES GAMMADELTA THERAPEUTICS LTD (GB) 2024-06-26 EP disclosed
US-20210087528-A1 EXPANSION OF GAMMA DELTA T CELLS, COMPOSITIONS, AND METHODS OF USE THEREOF KING'S COLLEGE LONDON (GB) 2021-03-25 US disclosed
WO-2021032961-A1 EX VIVO GAMMA DELTA T CELL POPULATIONS GammaDelta Therapeutics Limited (GB) 2021-02-25 WO disclosed
WO-2021032960-A1 NOVEL ANTI-TCR DELTA VARIABLE 1 ANTIBODIES GammaDelta Therapeutics Limited (GB) 2021-02-25 WO disclosed
WO-2021032963-A1 THERAPEUTIC USES OF ANTI-TCR DELTA VARIABLE 1 ANTIBODIES GammaDelta Therapeutics Limited (GB) 2021-02-25 WO disclosed
EP-3619298-A2 EXPANSION OF GAMMA DELTA T CELLS, COMPOSITIONS, AND METHODS OF USE THEREOF King's College London (GB) 2020-03-11 EP disclosed
WO-2018202808-A9 EXPANSION OF GAMMA DELTA T CELLS, COMPOSITIONS, AND METHODS OF USE THEREOF KING'S COLLEGE, LONDON (GB) 2019-03-07 WO disclosed
WO-2018202808-A2 EXPANSION OF GAMMA DELTA T CELLS, COMPOSITIONS, AND METHODS OF USE THEREOF KING'S COLLEGE, LONDON (GB) 2018-11-08 WO disclosed
US-20180312808-A1 EXPANSION OF NON-HAEMATOPOIETIC TISSUE-RESIDENT GAMMA DELTA T CELLS AND USES OF THESE CELLS CANCER RESEARCH TECHNOLOGY LIMITED (GB) 2018-11-01 US disclosed
EP-3368658-A1 EXPANSION OF NON-HAEMATOPOIETIC TISSUE-RESIDENT GAMMA DELTA T CELLS AND USES OF THESE CELLS Cancer Research Technology Limited (GB) 2018-09-05 EP disclosed
WO-2017072367-A1 EXPANSION OF NON-HAEMATOPOIETIC TISSUE-RESIDENT γδ T CELLS AND USES OF THESE CELLS CANCER RESEARCH TECHNOLOGY LIMITED (GB) 2017-05-04 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12637659-B2 Expansion of non-haematopoietic tissue-resident gamma delta T cells and uses of these cells IL15, IL15RA, IL2 BTN3A1 739/4885FNTA 1798/4885FNTB 888/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.