Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 1.00 |
| ▸ | CYP3A4 | P08684 | 1/20 | 1.00 |
| ▸ | CYP2C9 | P11712 | 1/20 | 1.00 |
| ▸ | CYP2C19 | P33261 | 1/20 | 1.00 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.85 |
| ▸ | LMNA | P02545 | 3/20 | 0.85 |
| ▸ | HPGD | P15428 | 3/20 | 0.85 |
| ▸ | RAB9A | P51151 | 1/20 | 0.77 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.73 |
| ▸ | TSHR | P16473 | 3/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.70 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.70 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18821435 | 0.86 | CYP1A2 (0.76) | CYP1A2CYP3A4CYP2C9CYP2C19KDM4E | |
| SCHEMBL18821167 | 0.86 | CYP1A2 (0.76) | CYP1A2CYP3A4CYP2C9CYP2C19KDM4E | |
| SCHEMBL18821160 | 0.86 | CYP1A2 (0.76) | CYP1A2CYP3A4CYP2C9CYP2C19KDM4E | |
| SCHEMBL18821302 | 0.85 | CYP1A2 (0.74) | CYP1A2CYP3A4CYP2C9CYP2C19KDM4E | |
| SCHEMBL18821169 | 0.84 | CYP1A2 (0.73) | CYP1A2CYP3A4CYP2C9CYP2C19KDM4E | |
| SCHEMBL18821182 | 0.84 | CYP1A2 (0.73) | CYP1A2CYP3A4CYP2C9CYP2C19KDM4E | |
| SCHEMBL18821436 | 0.83 | CYP1A2 (0.71) | CYP1A2CYP3A4CYP2C9CYP2C19KDM4E | |
| SCHEMBL18821158 | 0.83 | CYP1A2 (0.71) | CYP1A2CYP3A4CYP2C9CYP2C19KDM4E | |
| SCHEMBL3762247 | 0.78 | CYP1A2 (0.64) | CYP1A2CYP3A4CYP2C9CYP2C19KDM4E | |
| SCHEMBL3762594 | 0.78 | KMT2A (0.64) | CYP1A2CYP3A4CYP2C9CYP2C19KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230127633-A1 | INHIBITORS OF OXIDIZED LOW-DENSITY LIPOPROTEIN RECEPTOR 1 AND METHODS OF USE THEREOF | BIO VENTURES, LLC | 2023-04-27 | — | — | US | disclosed |
| US-20230127633-A1 | INHIBITORS OF OXIDIZED LOW-DENSITY LIPOPROTEIN RECEPTOR 1 AND METHODS OF USE THEREOF | BIO VENTURES, LLC | 2023-04-27 | — | — | US | disclosed |
| US-20230127633-A1 | INHIBITORS OF OXIDIZED LOW-DENSITY LIPOPROTEIN RECEPTOR 1 AND METHODS OF USE THEREOF | BIO VENTURES, LLC | 2023-04-27 | — | — | US | disclosed |
| US-11465972-B2 | Inhibitors of oxidized low-density lipoprotein receptor 1 and methods of use thereof | THE UNITED STATES GOVERNMENT AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS (US) | 2022-10-11 | — | — | US | disclosed |
| US-20200123112-A1 | INHIBITORS OF OXIDIZED LOW-DENSITY LIPOPROTEIN RECEPTOR 1 AND METHODS OF USE THEREOF | BIO VENTURES, LLC | 2020-04-23 | — | — | US | disclosed |
| US-20200123112-A1 | INHIBITORS OF OXIDIZED LOW-DENSITY LIPOPROTEIN RECEPTOR 1 AND METHODS OF USE THEREOF | BIO VENTURES, LLC | 2020-04-23 | — | — | US | disclosed |
| US-20180305318-A1 | INHIBITORS OF OXIDIZED LOW-DENSITY LIPOPROTEIN RECEPTOR 1 AND METHODS OF USE THEREOF | BIO VENTURES, LLC | 2018-10-25 | — | — | US | disclosed |
| WO-2017075418-A1 | INHIBITORS OF OXIDIZED LOW-DENSITY LIPOPROTEIN RECEPTOR 1 AND METHODS OF USE THEREOF | BOARD OF TRUSTEES OF THE UNIVERSITY OF ARKANSAS (US) | 2017-05-04 | — | — | WO | disclosed |
| WO-2017075418-A1 | INHIBITORS OF OXIDIZED LOW-DENSITY LIPOPROTEIN RECEPTOR 1 AND METHODS OF USE THEREOF | BOARD OF TRUSTEES OF THE UNIVERSITY OF ARKANSAS (US) | 2017-05-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200123112-A1 | INHIBITORS OF OXIDIZED LOW-DENSITY LIPOPROTEIN RECEPTOR 1 AND METHODS OF USE THEREOF | LDLR, LOX, LOXL1 | CYP1A2 905/4885CYP3A4 1452/4885CYP2C9 1627/4885 |
| US-20230127633-A1 | INHIBITORS OF OXIDIZED LOW-DENSITY LIPOPROTEIN RECEPTOR 1 AND METHODS OF USE THEREOF | LDLR, LOX, LOXL1 | CYP1A2 905/4885CYP3A4 1452/4885CYP2C9 1627/4885 |
| US-11465972-B2 | Inhibitors of oxidized low-density lipoprotein receptor 1 and methods of use thereof | LDLR, LOX, LOXL1 | CYP1A2 905/4885CYP3A4 1452/4885CYP2C9 1627/4885 |
| US-20180305318-A1 | INHIBITORS OF OXIDIZED LOW-DENSITY LIPOPROTEIN RECEPTOR 1 AND METHODS OF USE THEREOF | LDLR, LOX, LOXL1 | CYP1A2 905/4885CYP3A4 1452/4885CYP2C9 1627/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.