Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | BCHE | P06276 | 2/20 | 0.40 |
| ▸ | ACHE | P22303 | 2/20 | 0.40 |
| ▸ | TACR2 | P21452 | 3/20 | 0.39 |
| ▸ | CTSV | O60911 | 1/20 | 0.36 |
| ▸ | CTSL | P07711 | 1/20 | 0.36 |
| ▸ | CTSB | P07858 | 1/20 | 0.36 |
| ▸ | CTSS | P25774 | 1/20 | 0.36 |
| ▸ | CTSK | P43235 | 1/20 | 0.36 |
| ▸ | CTSC | P53634 | 1/20 | 0.36 |
| ▸ | CTSF | Q9UBX1 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | NT5E | P21589 | 1/20 | 0.35 |
| ▸ | AKT1 | P31749 | 1/20 | 0.35 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.35 |
| ▸ | CCKBR | P32239 | 1/20 | 0.34 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18815488 | 1.00 | LMNA (0.42) | LMNABCHEACHETACR2CTSV | |
| SCHEMBL30901679 | 1.00 | LMNA (0.42) | LMNABCHEACHETACR2CTSV | |
| SCHEMBL30284435 | 1.00 | LMNA (0.42) | LMNABCHEACHETACR2CTSV | |
| SCHEMBL23278051 | 0.84 | LMNA (0.42) | LMNABCHEACHETACR2CTSV | |
| SCHEMBL18816735 | 0.84 | LMNA (0.42) | LMNABCHEACHETACR2CTSV | |
| SCHEMBL18797789 | 0.84 | LMNA (0.42) | LMNABCHEACHETACR2CTSV | |
| SCHEMBL3300637 | 0.78 | LMNA (0.41) | LMNABCHEACHETACR2CTSV | |
| SCHEMBL24168933 | 0.78 | LMNA (0.41) | LMNABCHEACHETACR2CTSV | |
| SCHEMBL14817052 | 0.78 | LMNA (0.41) | LMNABCHEACHETACR2CTSV | |
| SCHEMBL1316508 | 0.76 | LMNA (0.40) | LMNABCHEACHETACR2CTSV |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190077797-A1 | PROCESSES FOR PREPARING 2-DIHALO RIBOLACTONES | EMORY UNIVERSITY | 2019-03-14 | — | — | US | disclosed |
| WO-2017075590-A2 | PROCESSES FOR PREPARING 2-DIHALO RIBOLACTONES | COCRYSTAL PHARMA, INC. (US) | 2017-05-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190077797-A1 | PROCESSES FOR PREPARING 2-DIHALO RIBOLACTONES | DERA, DPYD, DUS2 | LMNA 2095/4885BCHE 2748/4885ACHE 2683/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.