Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYMP | P19971 | 3/20 | 0.37 |
| ▸ | GAPDH | P04406 | 1/20 | 0.33 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.33 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.33 |
| ▸ | P2RY12 | Q9H244 | 4/20 | 0.31 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | NT5E | P21589 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18490592 | 0.98 | TYMP (0.37) | TYMPGAPDHTAS1R3TAS1R1P2RY12 | |
| SCHEMBL22301451 | 0.97 | TYMP (0.38) | TYMPGAPDHTAS1R3TAS1R1P2RY12 | |
| SCHEMBL18992202 | 0.97 | TYMP (0.38) | TYMPGAPDHTAS1R3TAS1R1P2RY12 | |
| SCHEMBL18048088 | 0.95 | TYMP (0.40) | TYMPGAPDHTAS1R3TAS1R1P2RY12 | |
| SCHEMBL18797900 | 0.95 | TYMP (0.39) | TYMPGAPDHTAS1R3TAS1R1P2RY12 | |
| SCHEMBL18797879 | 0.94 | TYMP (0.39) | TYMPGAPDHTAS1R3TAS1R1P2RY12 | |
| SCHEMBL22301448 | 0.94 | TYMP (0.39) | TYMPGAPDHTAS1R3TAS1R1P2RY12 | |
| SCHEMBL18917302 | 0.93 | KDM4E (0.37) | GAPDHTAS1R3TAS1R1P2RY12PRMT6 | |
| SCHEMBL18917307 | 0.93 | KDM4E (0.37) | GAPDHTAS1R3TAS1R1P2RY12PRMT6 | |
| SCHEMBL18797869 | 0.93 | TYMP (0.39) | TYMPGAPDHP2RY12PRMT6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3368072-A1 | COMPOSITIONS AND METHODS FOR ACTIVATING \"STIMULATOR OF INTERFERON GENE\"-DEPENDENT SIGNALLING | Aduro BioTech, Inc. (US) | 2018-09-05 | — | — | EP | disclosed |
| WO-2017075477-A1 | COMPOSITIONS AND METHODS FOR ACTIVATING \"STIMULATOR OF INTERFERON GENE\"-DEPENDENT SIGNALLING | Aduro Biotech, Inc. (US) | 2017-05-04 | — | — | WO | disclosed |