Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYMP | P19971 | 3/20 | 0.38 |
| ▸ | GAPDH | P04406 | 1/20 | 0.34 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.34 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.34 |
| ▸ | P2RY12 | Q9H244 | 5/20 | 0.32 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22301451 | 0.99 | TYMP (0.38) | TYMPGAPDHTAS1R3TAS1R1P2RY12 | |
| SCHEMBL18797906 | 0.97 | TYMP (0.37) | TYMPGAPDHTAS1R3TAS1R1P2RY12 | |
| SCHEMBL18490592 | 0.96 | TYMP (0.37) | TYMPGAPDHTAS1R3TAS1R1P2RY12 | |
| SCHEMBL22301448 | 0.96 | TYMP (0.39) | TYMPGAPDHTAS1R3TAS1R1P2RY12 | |
| SCHEMBL24602230 | 0.93 | TYMP (0.40) | TYMPGAPDHP2RY12PRMT6 | |
| SCHEMBL18048088 | 0.92 | TYMP (0.40) | TYMPGAPDHTAS1R3TAS1R1P2RY12 | |
| SCHEMBL18797900 | 0.91 | TYMP (0.39) | TYMPGAPDHTAS1R3TAS1R1P2RY12 | |
| SCHEMBL18797879 | 0.91 | TYMP (0.39) | TYMPGAPDHTAS1R3TAS1R1P2RY12 | |
| SCHEMBL22301424 | 0.91 | KDM4E (0.39) | GAPDHTAS1R3TAS1R1P2RY12PRMT6 | |
| SCHEMBL18992206 | 0.91 | TYMP (0.40) | TYMPGAPDHP2RY12PRMT6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180369268-A1 | METHODS FOR IDENTIFYING INHIBITORS OF \"STIMULATOR OF INTERFERON GENE\"- DEPENDENT INTERFERON PRODUCTION | Aduro Biotech, Inc. (US) | 2018-12-27 | — | — | US | disclosed |
| WO-2017106740-A1 | METHODS FOR IDENTIFYING INHIBITORS OF \"STIMULATOR OF INTERFERON GENE\"-DEPENDENT INTERFERON PRODUCTION | Aduro Biotech, Inc. (US) | 2017-06-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180369268-A1 | METHODS FOR IDENTIFYING INHIBITORS OF \"STIMULATOR OF INTERFERON GENE\"- DEPENDENT INTERFERON PRODUCTION | STING1, CGAS, IRF3 | TYMP 438/4885GAPDH 2281/4885TAS1R3 1553/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.