Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 4/20 | 0.34 |
| ▸ | MTNR1B | P49286 | 4/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18797979 | 0.89 | MTNR1A (0.35) | MTNR1AMTNR1BCYP1A2ALOX15MAPT | |
| SCHEMBL22667424 | 0.87 | MTNR1A (0.34) | MTNR1AMTNR1BCYP1A2ALOX15MAPT | |
| SCHEMBL23130214 | 0.83 | MTNR1A (0.33) | MTNR1AMTNR1BCYP1A2ALOX15MAPT | |
| SCHEMBL23130258 | 0.83 | MTNR1A (0.32) | MTNR1AMTNR1BCYP1A2ALOX15MAPT | |
| SCHEMBL21539650 | 0.83 | MTNR1A (0.35) | MTNR1AMTNR1BCYP1A2ALOX15MAPT | |
| SCHEMBL19228029 | 0.82 | MTNR1A (0.32) | MTNR1AMTNR1BCYP1A2ALOX15MAPT | |
| SCHEMBL19663689 | 0.82 | — | — | |
| SCHEMBL18797981 | 0.82 | MTNR1A (0.32) | MTNR1AMTNR1B | |
| SCHEMBL19228047 | 0.82 | MTNR1A (0.32) | MTNR1AMTNR1BCYP1A2ALOX15MAPT | |
| SCHEMBL19662835 | 0.82 | MTNR1A (0.31) | MTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9637504-B2 | Beta-lactamase inhibitors | VenatoRx Pharmaceuticals, Inc. (US) | 2017-05-02 | — | — | US | disclosed |