SCHEMBL18798570

SCHEMBL18798570

c1ccc(-c2cccc(N(c3cc(N(c4cccc(-c5ccccc5)c4)c4cccc5c4oc4ccccc45)c4ccc5cccc6ccc3c4c65)c3cccc4c3oc3ccccc34)c2)cc1

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 6/20 0.35
CYP1A1 P04798 5/20 0.35
CYP1B1 Q16678 4/20 0.35
ALOX5 P09917 3/20 0.33
CYP19A1 P11511 2/20 0.33
FYN P06241 2/20 0.32
AHR P35869 2/20 0.32
ERBB2 P04626 1/20 0.32
MAOA P21397 1/20 0.32
ACHE P22303 1/20 0.32
PLA2G2A P14555 3/20 0.32
PLA2G4A P47712 3/20 0.32
ABCG2 Q9UNQ0 2/20 0.32
KDM4E B2RXH2 1/20 0.32
PDE5A O76074 1/20 0.32
ALDH1A1 P00352 1/20 0.32
TP53 P04637 1/20 0.32
ABCB1 P08183 1/20 0.32
CYP3A4 P08684 1/20 0.32
CYP2D6 P10635 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20696437 0.94 CYP1A2 (0.35) CYP1A2CYP1A1CYP1B1ALOX5CYP19A1
SCHEMBL18798632 0.93 CYP19A1 (0.35) CYP1A2CYP1A1CYP1B1ALOX5CYP19A1
SCHEMBL4084581 0.92 ALOX5 (0.34) CYP1A2CYP1A1CYP1B1ALOX5CYP19A1
SCHEMBL18798581 0.92 ALOX5 (0.34) CYP1A2CYP1A1CYP1B1ALOX5CYP19A1
SCHEMBL18101711 0.92 CYP1A2 (0.36) CYP1A2CYP1A1CYP1B1ALOX5CYP19A1
SCHEMBL18101510 0.91 CYP1A1 (0.33) CYP1A2CYP1A1CYP1B1ALOX5KDM4E
SCHEMBL23849224 0.91 ALOX5 (0.33) CYP1A2CYP1A1CYP1B1ALOX5CYP19A1
SCHEMBL18101539 0.89 CYP1A1 (0.32) CYP1A2CYP1A1CYP1B1
SCHEMBL18101584 0.89 CYP1A1 (0.32) CYP1A2CYP1A1CYP1B1
SCHEMBL23849426 0.89 ALOX5 (0.36) CYP1A2CYP1A1CYP1B1ALOX5CYP19A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9640773-B2 Aromatic amine derivative and organic electroluminescence element using same IDEMITSU KOSAN CO., LTD. (JP) 2017-05-02 US disclosed
US-9640773-B2 Aromatic amine derivative and organic electroluminescence element using same IDEMITSU KOSAN CO., LTD. (JP) 2017-05-02 US disclosed