SCHEMBL18798574

SCHEMBL18798574

c1cc2ccc3c(N(c4cccc5c4oc4ccccc45)c4cccc5c4oc4ccccc45)cc(N(c4cccc5c4oc4ccccc45)c4cccc5c4oc4ccccc45)c4ccc(c1)c2c34

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AHR P35869 4/20 0.39
CYP1A2 P05177 3/20 0.39
MAOA P21397 2/20 0.39
ERBB2 P04626 1/20 0.39
FYN P06241 1/20 0.39
ACHE P22303 1/20 0.39
TDP1 Q9NUW8 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
ALOX5 P09917 3/20 0.38
ALDH1A1 P00352 4/20 0.34
HPGD P15428 4/20 0.34
HSD17B10 Q99714 2/20 0.34
THRB P10828 1/20 0.34
KDM4E B2RXH2 3/20 0.34
MEN1 O00255 2/20 0.34
MAPT P10636 2/20 0.34
KMT2A Q03164 2/20 0.34
NPC1 O15118 2/20 0.33
RAB9A P51151 2/20 0.33
CYP2C9 P11712 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18101711 0.92 CYP1A2 (0.36) AHRCYP1A2MAOAERBB2FYN
SCHEMBL20696442 0.91 CYP1A2 (0.39) AHRCYP1A2MAOAERBB2FYN
SCHEMBL18798578 0.90 ALOX5 (0.39) AHRCYP1A2MAOAERBB2FYN
SCHEMBL18101524 0.89 KDM4E (0.35) AHRCYP1A2MAOAERBB2FYN
SCHEMBL20696443 0.89 TDP1 (0.39) AHRCYP1A2MAOAERBB2FYN
SCHEMBL18798592 0.88 ALOX5 (0.37) AHRCYP1A2MAOAERBB2FYN
SCHEMBL4083821 0.88 ALOX5 (0.37) AHRCYP1A2MAOAERBB2FYN
SCHEMBL18101508 0.88 TDP1 (0.35) AHRCYP1A2MAOAERBB2FYN
SCHEMBL18798585 0.88 CYP1A2 (0.34) AHRCYP1A2MAOAERBB2FYN
SCHEMBL4078954 0.87 TDP1 (0.40) AHRCYP1A2MAOAERBB2FYN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9640773-B2 Aromatic amine derivative and organic electroluminescence element using same IDEMITSU KOSAN CO., LTD. (JP) 2017-05-02 US disclosed
US-9640773-B2 Aromatic amine derivative and organic electroluminescence element using same IDEMITSU KOSAN CO., LTD. (JP) 2017-05-02 US disclosed