Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 9/20 | 0.73 |
| ▸ | NAALAD2 | Q9Y3Q0 | 2/20 | 0.51 |
| ▸ | RIMKLA | Q8IXN7 | 1/20 | 0.51 |
| ▸ | CPB2 | Q96IY4 | 8/20 | 0.51 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21342528 | 0.93 | FOLH1 (0.80) | FOLH1NAALAD2RIMKLACPB2 | |
| SCHEMBL13019243 | 0.93 | FOLH1 (0.80) | FOLH1NAALAD2RIMKLACPB2 | |
| SCHEMBL11986386 | 0.93 | FOLH1 (0.80) | FOLH1NAALAD2RIMKLACPB2SLC6A5 | |
| SCHEMBL23839908 | 0.91 | FOLH1 (0.87) | FOLH1NAALAD2RIMKLACPB2SLC6A5 | |
| SCHEMBL4669761 | 0.85 | FOLH1 (1.00) | FOLH1NAALAD2RIMKLA | |
| SCHEMBL15739333 | 0.85 | FOLH1 (1.00) | FOLH1NAALAD2RIMKLA | |
| SCHEMBL2450656 | 0.85 | FOLH1 (1.00) | FOLH1NAALAD2RIMKLA | |
| SCHEMBL19265779 | 0.85 | FOLH1 (0.61) | FOLH1NAALAD2RIMKLACPB2 | |
| SCHEMBL15739351 | 0.85 | FOLH1 (1.00) | FOLH1NAALAD2RIMKLA | |
| SCHEMBL2450650 | 0.85 | FOLH1 (1.00) | FOLH1NAALAD2RIMKLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9636413-B2 | Conjugates for treating diseases caused by PSMA expressing cells | ENDOCYTE, INC. (US) | 2017-05-02 | — | — | US | disclosed |