Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 6/20 | 0.61 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.45 |
| ▸ | BLM | P54132 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | THRB | P10828 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | PLG | P00747 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
| ▸ | NAALAD2 | Q9Y3Q0 | 2/20 | 0.43 |
| ▸ | RIMKLA | Q8IXN7 | 1/20 | 0.43 |
| ▸ | GABRP | O00591 | 3/20 | 0.42 |
| ▸ | GABRD | O14764 | 3/20 | 0.42 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13019243 | 0.89 | FOLH1 (0.80) | FOLH1NAALAD2RIMKLACPB2 | |
| SCHEMBL21342528 | 0.89 | FOLH1 (0.80) | FOLH1NAALAD2RIMKLACPB2 | |
| SCHEMBL11986386 | 0.89 | FOLH1 (0.80) | FOLH1NAALAD2RIMKLACPB2 | |
| SCHEMBL18800237 | 0.85 | FOLH1 (0.73) | FOLH1NAALAD2RIMKLACPB2 | |
| SCHEMBL2742770 | 0.84 | FOLH1 (0.48) | FOLH1CYP2D6NFKB1BLMNPSR1 | |
| SCHEMBL20160962 | 0.82 | FOLH1 (0.44) | FOLH1KMT2AALDH1A1GSRRNPEP | |
| SCHEMBL15828219 | 0.79 | GABRP (0.42) | FOLH1NAALAD2RIMKLAGABRPGABRD | |
| SCHEMBL15739351 | 0.76 | FOLH1 (1.00) | FOLH1NAALAD2RIMKLA | |
| SCHEMBL4669761 | 0.76 | FOLH1 (1.00) | FOLH1NAALAD2RIMKLA | |
| SCHEMBL2450656 | 0.76 | FOLH1 (1.00) | FOLH1NAALAD2RIMKLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2644594-B1 | Cancer Cell Targeting Using Nanoparticles | PFIZER (US) | 2017-08-23 | — | — | EP | disclosed |