Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2C | P18825 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12670022 | 0.68 | ADRA2C (0.36) | ADRA2CMAPK1KMT2A | |
| SCHEMBL11236393 | 0.64 | KMT2A (0.33) | ADRA2CMAPK1KMT2A | |
| SCHEMBL11244184 | 0.60 | — | — | |
| SCHEMBL223179 | 0.59 | ADRA2C (0.56) | ADRA2CMAPK1KMT2A | |
| SCHEMBL21203108 | 0.59 | — | — | |
| SCHEMBL10746679 | 0.59 | ADRA2C (0.56) | ADRA2CMAPK1KMT2A | |
| SCHEMBL10746690 | 0.59 | ADRA2C (0.56) | ADRA2CMAPK1KMT2A | |
| SCHEMBL24938743 | 0.59 | GAA (0.33) | — | |
| SCHEMBL20080244 | 0.59 | ADRA2C (0.31) | ADRA2C | |
| SCHEMBL16450781 | 0.59 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9637462-B2 | Process for the preparation of N-iodoamides | TECHNION RESEARCH & DEVELOPMENT FOUNDATION LIMITED (IL) | 2017-05-02 | — | — | US | disclosed |