⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1146593 | 0.82 | — | — | |
| Methylene Chloride SCHEMBL1413436 | 0.78 | — | — | |
| Water SCHEMBL2395414 | 0.77 | — | — | |
| Hydrochloric Acid SCHEMBL27913501 | 0.77 | — | — | |
| SCHEMBL28333397 | 0.77 | — | — | |
| Chloroform SCHEMBL7263215 | 0.67 | — | — | |
| SCHEMBL926283 | 0.64 | — | — | |
| Chloroform SCHEMBL7542885 | 0.64 | TSHR (0.60) | — | |
| Chloroform SCHEMBL2819782 | 0.64 | TSHR (0.60) | — | |
| Chloroform SCHEMBL8192102 | 0.64 | TSHR (0.60) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2939695-B1 | POLYMERIC COUPLING AGENTS AND PHARMACEUTICALLY-ACTIVE POLYMERS MADE THEREFROM | INTERFACE BIOLOGICS INC (CA) | 2018-08-29 | — | — | EP | disclosed |
| EP-2939695-A1 | POLYMERIC COUPLING AGENTS AND PHARMACEUTICALLY-ACTIVE POLYMERS MADE THEREFROM | Interface Biologics Inc. (CA) | 2015-11-04 | — | — | EP | disclosed |
| US-20130289223-A1 | POLYMERIC COUPLING AGENTS AND PHARMACEUTICALLY-ACTIVE POLYMERS MADE THEREFROM | INTERFACE BIOLOGICS INC. (CA) | 2013-10-31 | — | — | US | disclosed |
| US-8349309-B2 | Polymeric coupling agents and pharmaceutically-active polymers made therefrom | INTERFACE BIOLOGICS INC. (CA) | 2013-01-08 | — | — | US | disclosed |
| US-20110112259-A1 | POLYMERIC COUPLING AGENTS AND PHARMACEUTICALLY-ACTIVE POLYMERS MADE THEREFROM | INTERFACE BIOLOGICS, INC (CA) | 2011-05-12 | — | — | US | disclosed |
| EP-1744787-A1 | POLYMERIC COUPLING AGENTS AND PHARMACEUTICALLY-ACTIVE POLYMERS MADE THEREFROM | Interface Biologics Inc. (CA) | 2007-01-24 | — | — | EP | disclosed |
| WO-2005110485-A1 | POLYMERIC COUPLING AGENTS AND PHARMACEUTICALLY-ACTIVE POLYMERS MADE THEREFROM | INTERFACE BIOLOGICS INC. (CA) | 2005-11-24 | — | — | WO | disclosed |
| US-20050255082-A1 | Polymeric coupling agents and pharmaceutically-active polymers made therefrom | INTERFACE BIOLOGICS INC. (CA) | 2005-11-17 | — | — | US | disclosed |
| US-20030229076-A1 | Substituted imidazoles as selective modulators of bradykinin B2 receptors | RACHWAL STANISLAW (US) | 2003-12-11 | — | — | US | disclosed |
| US-6660263-B2 | Mono-chlorinated lipophilic macrocyclic lactone isolated from a strain of Serratia marcescens that produces oocydin A in culture. | HMV CORPORATION | 2003-12-09 | — | — | US | disclosed |
| US-6509366-B2 | Substituted imidazoles as selective modulators of Bradykinin B2 receptors | NEUROGEN CORPORATION | 2003-01-21 | — | — | US | disclosed |
| US-6482844-B1 | 1-benzylimidazole derivatives | NEUROGEN CORPORATION | 2002-11-19 | — | — | US | disclosed |
| US-20020115693-A1 | Substituted imidazoles as selective modulators of bradykinin B2 receptors | NEUROGEN CORPORATION | 2002-08-22 | — | — | US | disclosed |
| US-20020032308-A1 | Oocydin and methods of use for protection of plants from Oomyocyte pathogens | HMV CORPORATION | 2002-03-14 | — | — | US | disclosed |
| WO-2001056995-A1 | SUBSTITUTED IMIDAZOLES AS SELECTIVE MODULATORS OF BRADYKININ B2 RECEPTORS | NUEROGEN CORPORATION (US) | 2001-08-09 | — | — | WO | disclosed |
| US-4885292-A | HYPOTENSIVE AGENTS | E. R. SQUIBB & SONS, INC. (US) | 1989-12-05 | — | — | US | disclosed |