Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 4/20 | 0.36 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18800876 | 1.00 | TSHR (0.40) | TSHRTHRBHSD17B10GAADNM1 | |
| SCHEMBL18800905 | 1.00 | TSHR (0.40) | TSHRTHRBHSD17B10GAADNM1 | |
| SCHEMBL11838574 | 0.90 | HSD17B10 (0.45) | TSHRTHRBHSD17B10GAA | |
| SCHEMBL18197771 | 0.85 | HSD17B10 (0.42) | HSD17B10GAA | |
| SCHEMBL22423629 | 0.82 | TRPV1 (0.44) | TSHRHSD17B10 | |
| SCHEMBL18800950 | 0.80 | HTT (0.37) | THRB | |
| SCHEMBL15786649 | 0.80 | HSD17B10 (0.42) | HSD17B10GAA | |
| SCHEMBL23996260 | 0.78 | HSD17B10 (0.41) | TSHRTHRBHSD17B10GAA | |
| SCHEMBL19689040 | 0.78 | HSD17B10 (0.41) | TSHRTHRBHSD17B10GAA | |
| SCHEMBL30150908 | 0.78 | HSD17B10 (0.38) | HSD17B10DNM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3162794-A1 | CATIONIC LIPID | Kyowa Hakko Kirin Co., Ltd. (JP) | 2017-05-03 | — | — | EP | disclosed |