Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | CES1 | P23141 | 1/20 | 0.36 |
| ▸ | CES2 | O00748 | 2/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.32 |
| ▸ | GBA1 | P04062 | 4/20 | 0.32 |
| ▸ | GBA2 | Q9HCG7 | 8/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22423634 | 0.88 | ALDH1A1 (0.36) | ALDH1A1EPHX2 | |
| SCHEMBL20307879 | 0.87 | HTT (0.38) | HTTMEN1THRBKMT2AMAPT | |
| SCHEMBL18800894 | 0.85 | MEN1 (0.44) | HTTMEN1THRBKMT2AMAPT | |
| SCHEMBL18800899 | 0.80 | TSHR (0.40) | THRB | |
| SCHEMBL18800876 | 0.80 | TSHR (0.40) | THRB | |
| SCHEMBL22367682 | 0.79 | TSHR (0.35) | — | |
| SCHEMBL18800993 | 0.78 | ALDH1A1 (0.43) | ALDH1A1 | |
| SCHEMBL28774497 | 0.75 | ALDH1A1 (0.37) | HTTMEN1THRBKMT2AMAPT | |
| SCHEMBL28774513 | 0.73 | SMN1; SMN2 (0.36) | HTTMEN1THRBKMT2AMAPT | |
| SCHEMBL17923840 | 0.72 | HTT (0.41) | HTTMEN1THRBKMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3162794-A1 | CATIONIC LIPID | Kyowa Hakko Kirin Co., Ltd. (JP) | 2017-05-03 | — | — | EP | disclosed |